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Myrcludex B
go.drugbank.com/drugs/DB14853InvestigationalMyrcludex B is under investigation in clinical trial NCT03546621 (A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination … With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D).
Ofirnoflast
go.drugbank.com/drugs/DB21679InvestigationalOfirnoflast is under investigation in clinical trial NCT07052006 (HT-6184 in Subjects With MDS). Ofirnoflast has a monoisotopic molecular weight of 501.15 Da. … The usage of the INN stem '-noflast' in the name indicates that Ofirnoflast is a inflammasome protein NLRP3 inhibitor.
Lurtotecan
go.drugbank.com/drugs/DB12222InvestigationalLurtotecan is under investigation in clinical trial NCT00022594 (Liposomal Lurtotecan in Treating Patients With Metastatic or Locally Recurrent Head and Neck Cancer).
Lanraplenib
go.drugbank.com/drugs/DB14770InvestigationalLanraplenib is under investigation in clinical trial NCT03285711 (Safety and Efficacy of Filgotinib and Lanraplenib in Adults With Lupus Membranous Nephropathy (LMN)).
Afasevikumab
go.drugbank.com/drugs/DB14798InvestigationalAfasevikumab is under investigation in clinical trial NCT01480310 (Study to Investigate the Safety, Pharmacokinetics, and Immunogenicity of Subcutaneous MCAF5352A in Healthy Volunteers).
BIO-11006
go.drugbank.com/drugs/DB14886InvestigationalBIO-11006 is under investigation in clinical trial NCT03202394 (Evaluation of Safety & Efficacy of BIO-11006 Inhalation Solution in Patients With ARDS).
Recombinant CD40-ligand
go.drugbank.com/drugs/DB15015InvestigationalRecombinant CD40-ligand is under investigation in clinical trial NCT00053391 (Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma).
Flutriciclamide F-18
go.drugbank.com/drugs/DB15380ExperimentalFlutriciclamide F-18 is under investigation in clinical trial NCT02350426 (A Study to Assess Inflammation in Rheumatoid Arthritis Using Molecular Imaging Techniques).
GSK-3117391
go.drugbank.com/drugs/DB15440InvestigationalGSK-3117391 is under investigation in clinical trial NCT02965599 (Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GSK3117391 in Subjects With Rheumatoid Arthritis).
AZD8529
go.drugbank.com/drugs/DB16073InvestigationalAZD8529 is under investigation in clinical trial NCT00921804 (Study to Assess the Efficacy, Safety, and Tolerability of AZD8529 in Adult Schizophrenia Patients).