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ATIR101
go.drugbank.com/drugs/DB18650InvestigationalATIR101 is a haploidentical, naïve cell-enriched T-cell therapy.
ssCART-19 cells
go.drugbank.com/drugs/DB18653InvestigationalssCART-19 cells consist of autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6).
Synonyms: autologous anti-CD19 Chimeric Antigen Receptors (CAR)-T cells expressing a short hairpin RNA (shRNA) against interleukin-6 (IL-6) (also termed ssCART-19 cells)Geptanolimab
go.drugbank.com/drugs/DB16417InvestigationalGeptanolimab is under investigation in clinical trial NCT03502629 (Clinical Trial in Chinese Patients of Relapsed and Refractory Peripheral T Cell Lymphoma (GB226)).
GI-101
go.drugbank.com/drugs/DB17243InvestigationalGI-101 is a bi-specific fragment crystallizable region (Fc) fusion protein containing a cluster of differentiation 80 ectodomain as an N-terminal moiety and interleukin-2 variant as a C-terminal moiety
Etentamig
go.drugbank.com/drugs/DB17268InvestigationalTNB-383B is a CD3 and B-cell maturation antigen T-cell engaging bispecific antibody.
Synonyms: Anti-BCMA x aCD3 T-BsAb TNB-383B, Anti-BCMA/Anti-CD3 T-cell Engaging Bispecific Antibody ABBV-383AMG-119
go.drugbank.com/drugs/DB17363InvestigationalAMG-119 are CAR-T cells targeting delta-like ligand 3 (DLL3).[A254811]
AUTO3
go.drugbank.com/drugs/DB17364InvestigationalIt is an investigational chimeric antigen receptor (CAR) T cell treatment targeting CD19 and CD22. … AUTO3 is bicistronic chimeric antigen receptor T-cell therapy investigated for acute lymphoblastic leukemia (ALL).
LioCyx-M004
go.drugbank.com/drugs/DB17368InvestigationalLioCyx-M004 are autologous T cells transduced with a retroviral vector encoding a hepatitis B virus antigen-specific T cell receptor.
Synonyms: mRNA HBV/TCR T-cellsP-BCMA-101
go.drugbank.com/drugs/DB17371InvestigationalP-BCMA-101 is an autologous CAR-T therapy developed using Poseida’s piggyBac platform technology.
Synonyms: Autologous T-cells transfected with PiggyBac transposon plasmid vector expressing B-cell maturation antigen (CAR-T cells)