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DNB-001
go.drugbank.com/drugs/DB05757InvestigationalDNB-001 is a first-in-class oral therapy with dual mechanism of action, which is initially being developed for the treatment of glaucoma. … In preclinical animal models, DNB-001 has demonstrated potent IOP- lowering effects as well as neuroprotective effects on the optic nerve.
Gemogenovatucel-T
go.drugbank.com/drugs/DB17412InvestigationalFurin is a convertase involved in the activation of TGFβ-1 and TGFβ-2.[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.
Synonyms: Gemogenovatucel-TOxalic Acid
go.drugbank.com/drugs/DB03902ExperimentalIt is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent. [PubChem]
PAC-113
go.drugbank.com/drugs/DB05756InvestigationalIn vitro studies demonstrate that it has potent anti-fungal activity against the Candida albicans, including drug-resistant HIV patient isolates. … PAC-113 an anti-fungal, for the treatment of oral candidiasis infections. It is a 12 amino-acid antimicrobial peptide derived from a naturally occurring histatin protein found in saliva.
Gisadenafil
go.drugbank.com/drugs/DB11902InvestigationalGisadenafil has been investigated for the treatment of Prostatic Hyperplasia.
Napabucasin
go.drugbank.com/drugs/DB12155InvestigationalNapabucasin has been investigated for the treatment of Colorectal Carcinoma.
Puerarin
go.drugbank.com/drugs/DB12290InvestigationalPuerarin has been investigated for the treatment of Alcohol Abuse.
Piclozotan
go.drugbank.com/drugs/DB12361InvestigationalPiclozotan has been investigated for the treatment of Parkinson's Disease.
Glyceryl Trierucate
go.drugbank.com/drugs/DB12528InvestigationalGlyceryl Trierucate has been investigated for the treatment of Adrenoleukodystrophy.
AZD-7295
go.drugbank.com/drugs/DB12724InvestigationalAZD7295 has been investigated for the treatment of Hepatitis C.