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Rovaleucel
go.drugbank.com/drugs/DB18691InvestigationalRovaleucel is an EBV-specific autologous T-cell therapy under investigation for the treatment of EBV-positive cancers.
Nelistotug
go.drugbank.com/drugs/DB19334InvestigationalNCT06062420 (A Platform Study of Novel Immunotherapy Combinations as First-line Treatment in Participants With PD-L1 Positive Recurrent/metastatic Squamous Cell Carcinoma of the Head and Neck- GALAXIES H&N-
Synonyms: Nelistotug (immunoglobulin G1-kappa, anti-[Homo sapiens CD96 (T cell activation increased late expression, TACTILE, T-cell surface protein tactile)], Homo sapiens monoclonal antibody), Gamma1 heavy chain Homo sapiens (1-452) [VH(Homo sapiens IGHV1-69*01 (95.9%) -(IGHD)-IGHJ1*01 (90.9%) L123>T (117), CDR-IMGT [8.8.15](26-33.51-58.97-111)) (1-122) -Homo sapiens IGHG1*01 (100%), G1m17,1Fluocortolone pivalate
go.drugbank.com/drugs/DB15777InvestigationalMixtures: ULTRAPROCT N, ULTRAPROCT NNNC-55-0396 free base
go.drugbank.com/drugs/DB17037ExperimentalNNC-55-0396 is a T-type Ca(2+) channel inhibitor.[A253047]
Gemogenovatucel-T
go.drugbank.com/drugs/DB17412Investigational[A255163] Gemogenovatucel-T is being investigated in the treatment of various cancers. … Gemogenovatucel-T is a bi-shRNA furin/Granulocyte Macrophage Colony Stimulating Factor (GMCSF) Augmented autologous tumour cell vaccine.
Synonyms: Gemogenovatucel-TErfonrilimab
go.drugbank.com/drugs/DB17446InvestigationalErfonrilimab is a bispecific monoclonal antibody directed against both the programmed cell death-1 ligand 1 (PD-L1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA4).
UCART22
go.drugbank.com/drugs/DB17466InvestigationalUCART22 are allogeneic CD22-specific universal CAR-expressing T lymphocytes.
Synonyms: Allogeneic gene-edited CAR T cells UCART22, Allogeneic TALEN gene-edited CAR T-Cells UCART22Tralesinidase alfa
go.drugbank.com/drugs/DB17657InvestigationalTralesinidase alfa is a chimeric fusion protein comprised of recombinant human NAGLU and a modified human insulin-like growth factor 2. It is being investigated for the treatment of mucopolysaccharidosis type IIIB (MPS IIIB), also known ...
Synonyms: Alpha-N-acetyglucosaminidase-insulin-like-growth-factor-2 fusion protein, Recombinant human alpha-N-acetylglucosaminidase-insulin-like growth factor-2Categories: beta-N-Acetylhexosaminidases