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Displaying results 731 - 740 of 10000 in total
  1. Drug

    1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea

    go.drugbank.com/drugs/DB04336
    Experimental

    Synonyms: 1-(4-Amidinophenyl)-3-(4-Chlorophenyl)Urea
  2. Drug

    4-Deoxy-4-Amino-Beta-D-Glucose

    go.drugbank.com/drugs/DB03291
    Experimental

    Synonyms: 4-Deoxy-4-Amino-Beta-D-Glucose
  3. Drug

    N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide

    go.drugbank.com/drugs/DB07734
    Experimental

    Synonyms: N-(1-benzylpiperidin-4-yl)-4-sulfanylbutanamide
  4. Drug

    MAX-40279

    go.drugbank.com/drugs/DB15191
    Investigational

    MAX-40279 is under investigation in clinical trial NCT03412292 (MAX-40279 in Subjects With Acute Myelogenous Leukemia (AML)).

    Synonyms: 7-(4-Fluoro-2-methoxyphenyl)-6-methyl-N-(1-(piperidin-4-yl)-1H-pyrazol-4-yl) thieno (3,2-d)pyrimidin-2-amine
  5. Drug

    EP-0042

    go.drugbank.com/drugs/DB18120
    Investigational

    Synonyms: 3H-IMIDAZO(4,5-B)PYRIDINE, 6-CHLORO-7-(4-((4-CHLOROPHENYL)METHYL)-1-PIPERAZINYL)-2-(1,3-DIMETHYL-1H-PYRAZOL-4-YL)-Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  6. Drug

    Landiolol

    go.drugbank.com/drugs/DB12212
    ApprovedInvestigational

    for β-1 adrenergic receptors over β-2 receptors. … Landiolol is a rapid-acting beta (β)-1 adrenergic receptor blocker that blocks the positive chronotropic effect of the beta-1 selective agonist norepinephrine.

    Synonyms: [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl 3-(4-{(2S)-2-hydroxy-3-[{2-[(morpholin-4-ylcarbonyl)amino]ethyl}amino]propoxy}phenyl)propanoate, Benzenepropanoic acid, 4-[(2S)-2-hydroxy-3-[[2-[(4-morpholinylcarbonyl)amino]ethyl]amino]propoxy]-, [(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl esterCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-Ring
  7. Drug

    Dasabuvir

    go.drugbank.com/drugs/DB09183
    Approved

    HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 being the most common in the United States, and affecting 72% of all chronic HCV patients [L852]. … in combination with [DB09296], [DB09297], and [DB00503] for genotype 1b and with [DB00811] for genotype 1a of Hepatitis C [L852].

    Synonyms: Sodium 3-(3-tert-butyl-4-methoxy-5-{6­ [(methylsulfonyl)amino]naphthalene-2-yl}phenyl)-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-ide hydrate (1:1:1), N-{6-[3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl]naphthalen-2-yl}methanesulfonamideCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  8. Drug

    Lesinurad

    go.drugbank.com/drugs/DB11560
    ApprovedWithdrawn

    Marketed as the product Zurampic, it is indicated for use in combination with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with gout in patients who have not achieved target … In August 2017, a combination oral therapy consisting of lesinurad and [DB00437] was FDA-approved under the brand name Duzallo indicated for the treatment of gout-related hyperuricemia in patients with

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid
  9. Drug

    LY-3499446

    go.drugbank.com/drugs/DB17486
    Investigational

    Synonyms: 1-(4-(7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoro-quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one, 2-propen-1-one, 1-(4-(7-2-amino-7-fluoro-4-benzothiazolyl)-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinyl)-
  10. Drug

    Terpinen-4-ol

    go.drugbank.com/drugs/DB12816
    Investigational

    Terpinen-4-ol is under investigation in clinical trial NCT01647217 (Demodex Blepharitis Treatment Study).

    Synonyms: Terpinen-4-olCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Substrates