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Risperidone
go.drugbank.com/drugs/DB00734ApprovedInvestigational[L12885] Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors, and carries lesser activity at several off-targets … [L12885] Schizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways
International brands: Risperidal M-TabCategories: Adrenergic alpha-1 Receptor Antagonists, Heterocyclic Compounds, 1-RingVardenafil
go.drugbank.com/drugs/DB00862ApprovedVardenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) and an oral therapy for the treatment of erectile dysfunction. During sexual stimulation, nitric oxide (NO) is released...
Categories: Heterocyclic Compounds, 1-RingProducts: LEVITRA TABLET 10 mg, LEVITRA 10 MG AGIZDA DAGILAN TABLET, 1 ADETAtosiban
go.drugbank.com/drugs/DB09059ApprovedInvestigationalAtobisan was developed by the Swedish company Ferring Pharmaceuticals. It was first reported in the literature in 1985.
Products: Atosiban EVER Pharma 75 mg/10 ml Konzentrat zur Herstellung einer Infusionslösung, TRACTOCILE 7,5 MG/ML ENJEKSIYONLUK ÇÖZELTİ, 0,9 ML FLAKON, 1 ADETVoriconazole
go.drugbank.com/drugs/DB00582ApprovedInvestigational[A236050] Voriconazole was approved by the FDA under the trade name Vfend on May 24, 2002.[L34660] … The increased affinity of voriconazole for 14-alpha sterol demethylase makes it useful against some [fluconazole]-resistant organisms.
Categories: 14-alpha Demethylase Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: (αR,βS)-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, (R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanolPerampanel
go.drugbank.com/drugs/DB08883ApprovedInvestigationalIt is marketed under the name Fycompa™ and is indicated as an adjunct in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(2-Cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-oneChloroquine
go.drugbank.com/drugs/DB00608ApprovedInvestigationalVet approved[A192432] **The FDA emergency use authorization for [hydroxychloroquine] and chloroquine in the treatment of COVID-19 was revoked on 15 June 2020.
Categories: Experimental Unapproved Treatments for COVID-19Products: KUTLU 250 MG FİLM KAPLI TABLET, 10 ADET, OROQUİNE 250 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ , 10 ADETMiglitol
go.drugbank.com/drugs/DB00491Approvedmonosaccharides which can be absorbed by the body. … Unlike other drugs of the same class, miglitol is not metabolized and the unmetabolized drug is excreted by the kidneys.
Mixtures: MEGLITIS 100/500MG EFERVESAN TABLET, 100 TABLET, MEGLITIS 100/850MG EFERVESAN TABLET, 100 TABLETCategories: Heterocyclic Compounds, 1-RingDiflunisal
go.drugbank.com/drugs/DB00861ApprovedDiflunisal, a salicylate derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with pharmacologic actions similar to other prototypical NSAIAs. Diflunisal possesses anti-inflammatory, analgesic and antipyretic activity. Though it...
Products: DOLPHIN 250 MG FILM TABLET, 10 TABLET, Diflimax 500 mg Film Kaplı Tablet (10 adet)Abemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity. On September 28, 2017, FDA gr...
Categories: MATE 1 Inhibitors, MATE 1 SubstratesProducts: VERZENIO® 100 MG, VERZENIO® 150 MGBetamethasone
go.drugbank.com/drugs/DB00443ApprovedInvestigationalVet approvedBetamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states inclu...
Mixtures: FUCICORT 20 MG/G + 1 MG/G KREM, 30 G, BRUMETON 1 MG/ML+100 MG/ML GÖZ DAMLASIProducts: XORSONE 1:10 Cream, BETAMETASONA 4 MG/ 1 ML INYECTABLE