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Displaying results 741 - 750 of 10000 in total
  1. Drug

    Donepezil

    go.drugbank.com/drugs/DB00843
    ApprovedInvestigational

    Donepezil was first approved by the FDA in 1996, and its extended-release form was approved in combination with [Memantine] in 2014 to manage moderate and severe forms of Alzheimer's dementia. … In 2016, the global burden of dementia was estimated to be 43.8 million, demonstrating a significant increase from a global prevalence of 20.2 million in 1990.

    Mixtures: EBICOMB 10 MG/10 MG EFERVESAN TABLET, 100 ADET, EBICOMB 5 MG/10 MG EFERVESAN TABLET, 100 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
  2. Drug

    Risankizumab

    go.drugbank.com/drugs/DB14762
    ApprovedInvestigational

    [A254716] Risankizumab is used to treat plaque psoriasis, psoriatic arthritis, and Crohn's disease.[L39885,L44191,L44231] Risankizumab is being investigated for atopic dermatitis.[A254716] … [L39885] It gained its first global approval in Japan in March 2019, followed by approval in Canada, the US, and Europe in April 2019.

    Products: Skyrizi 150 mg/ml Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 1 ADET, SKYRİZİ 150 MG/ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET
  3. Drug

    Methenamine

    go.drugbank.com/drugs/DB06799
    ApprovedInvestigationalVet approved

    Methenamine is a heterocyclic organic compound with a cage-like structure similar to adamantane.

    Mixtures: PURINOL 250 mg+615 mg/5 g EFERVESAN 140 GR, PURINOL 250 mg+615 mg/5 g EFERVESAN 140 GRProducts: URON 500 MG TABLET, 1000 ADET, URON 500 MG TABLET, 500 ADET
  4. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label][L771] and empty the large intestine before surgery. … The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label].

    Mixtures: Sennosides 8.6 Mg and Docusate Sodium 50 Mg Tablets, EUCARBON TABLET, 100 ADETProducts: ROHA LAX 20 MG/5 ML GRANÜL, 150 ML, X-M DİET 1,5 MG/ML ÇÖZELTİ, 150 ML
  5. Drug

    Triethylenetetramine

    go.drugbank.com/drugs/DB06824
    ApprovedInvestigational

    tolerant to [penicillamine]. … [A19333] Initially approved by the FDA in 1985 as a second-line treatment for Wilson's disease,[A19334] TETA is currently indicated to treat adults with stable Wilson’s disease who are de-coppered and

    Products: NOVİLS 250 MG SERT KAPSÜL, 100 ADET, WİLENTİN 250 MG SERT KAPSÜL, 100 ADET
  6. Drug

    Mirikizumab

    go.drugbank.com/drugs/DB14910
    ApprovedInvestigational

    Mirikizumab is a monoclonal antibody developed by Eli Lilly intended to treat ulcerative colitis. … [L46237] In April 2023, the US FDA declined to approve mirikizumab for the treatment of ulcerative colitis on the basis of manufacturing concerns.

    Products: Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 2 ADET, Misuvya 100 mg/1 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem, 6 ADET
  7. Drug

    Atorvastatin

    go.drugbank.com/drugs/DB01076
    ApprovedInvestigational

    [A181087, A181406] Some evidence has shown that even for low-risk individuals (with <10% risk of a major vascular event occurring within five years) statin use leads to a 20%-22% relative reduction in … More specifically, statin medications competitively inhibit the enzyme hydroxymethylglutaryl-coenzyme A (HMG-CoA) Reductase,[A181421] which catalyzes the conversion of HMG-CoA to mevalonic acid.

    Mixtures: ATOPIR 10 MG/100 MG KAPSUL, 30 ADET, Trinomia 100 mg/20 mg/10 mg HartkapselnCategories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 Substrates
  8. Drug

    Sulthiame

    go.drugbank.com/drugs/DB08329
    Approved

    Products: Sultiam neuraxpharm 100 mg Filmtabletten, Ospolot 50 mg Filmtabletten
  9. Drug

    Sotalol

    go.drugbank.com/drugs/DB00489
    ApprovedInvestigational

    Sotalol is a methanesulfonanilide developed in 1960.[A178579] It was the first of the class III anti arrhythmic drugs.[A178579] Sotalol was first approved as an oral tablet on 30 October 1992.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: SOTALEX 160 MG, PMS-sotalol - 160 mg
  10. Drug

    Propylthiouracil

    go.drugbank.com/drugs/DB00550
    Approved

    Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism.

    Products: TIROSTAT 100, PROPYL TABLET 50 mg