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Displaying results 7571 - 7580 of 10000 in total
  1. Drug

    Brincidofovir

    go.drugbank.com/drugs/DB12151
    ApprovedInvestigational

    [A235725,A235735] Due to its formulation as a pro-drug brincidofovir also carries a greater bioavailability than cidofovir,[A235740,A235725] allowing for oral administration rather than intravenous. … Brincidofovir is an oral antiviral drug used in the treatment of human smallpox infections.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Heterocyclic Compounds, 1-Ring
  2. Drug

    Citicoline

    go.drugbank.com/drugs/DB12153
    ApprovedInvestigationalWithdrawn

    Citicoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Cytidine 5'-diphosphocholine, Cytidine-5'-diphosphocholine
  3. Drug

    Napabucasin

    go.drugbank.com/drugs/DB12155
    Investigational

    Napabucasin has been investigated for the treatment of Colorectal Carcinoma.

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Fasinumab

    go.drugbank.com/drugs/DB12157
    Investigational

    Fasinumab is a human IgG1k monoclonal antibody targeted against nerve growth factor (NGF). … It is currently under investigation for the treatment osteoarthritic pain[A241045] and has demonstrated significantly greater pain relief and functional improvement as compared to standard therapy (i.e

  5. Drug

    Filorexant

    go.drugbank.com/drugs/DB12158
    Investigational

    Filorexant has been used in trials studying the prevention and treatment of Migraine, Headache, Polysomnography, Diabetic Neuropathy, Painful, and Major Depressive Disorder, Recurrent.

    Categories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Deutetrabenazine

    go.drugbank.com/drugs/DB12161
    ApprovedInvestigational

    Deutetrabenazine is a racemic mixture containing RR-Deutetrabenazine and SS-Deutetrabenazine [FDA Label]. … It is a hexahydro-dimethoxybenzoquinolizine derivative and a deuterated [DB04844] [A32046].

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  7. Drug

    Nimorazole

    go.drugbank.com/drugs/DB12172
    Investigational

    Nimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Apitolisib

    go.drugbank.com/drugs/DB12180
    Investigational

    Apitolisib has been used in trials studying the treatment of Solid Cancers, Breast Cancer, Prostate Cancer, Renal Cell Carcinoma, and Endometrial Carcinoma, among others.

    Categories: Heterocyclic Compounds, 1-Ring, Phosphatidylinositol 3-Kinases, antagonists & inhibitors
  9. Drug

    Dalcetrapib

    go.drugbank.com/drugs/DB12181
    Investigational

    Dalcetrapib is under investigation for the treatment of Acute Coronary Syndrome.

  10. Drug

    Abacavir hydroxyacetate

    go.drugbank.com/drugs/DB12187
    Investigational

    Prurisol is under investigation for the treatment of Chronic Stable Plaque Psoriasis. Prurisol has been investigated for the treatment of Plaque Psoriasis.

    Categories: Heterocyclic Compounds, 2-Ring