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Panitumumab
go.drugbank.com/drugs/DB01269ApprovedInvestigationalPanitumumab (ABX-EGF) is a recombinant human IgG2 monoclonal antibody that binds specifically to the human epidermal growth factor receptor (EGFR). This drug is an antineoplastic agent.
Products: Vectibix Concentrate for Solution for Infusion 100 mg/vial, VECTIBIX 20 MG/ML 5 ML IV INFUZYON ICIN COZELTI ICEREN FLAKON, 1 ADETCaspofungin
go.drugbank.com/drugs/DB00520ApprovedInvestigationalCaspofungin (brand name Cancidas worldwide) is an antifungal drug and the first member of a new drug class called the echinocandins, as coined by Merck & Co., Inc. … It shows activity against infections with Aspergillus and Candida, and works by inhibiting β(1,3)-D-Glucan of the fungal cell wall.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsSynonyms: (4R,5S)-5-((2-Aminoethyl)amino)-N(sup 2)-(10,12-dimethyltetradecanoyl)-4-hydroxy-L-ornithyl-L-threonyl-trans-4-hydroxy-L-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-L-threonyl-threo-3-hydroxy-L-ornithyl-transMelatonin
go.drugbank.com/drugs/DB01065ApprovedInvestigationalNutraceuticalVet approved) but outside the blood-brain barrier. … The secretion of melatonin increases in darkness and decreases during exposure to light, thereby regulating the circadian rhythms of several biological functions, including the sleep-wake cycle.
Synonyms: 5-methoxy-N-acetyl tryptamine, 5-methoxy-N-acetyltryptamineInternational brands: Mela-TInterferon alfa-2b
go.drugbank.com/drugs/DB00105ApprovedInvestigationalA type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes.
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules)Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsColchicine
go.drugbank.com/drugs/DB01394ApprovedInvestigationalColchicine is an alkaloid drug derived from a plant belonging to the Lily family, known as _Colchicum autumnale_, or "autumn crocus."[A183611] Its use was first approved by the FDA in 1961.
Categories: Preparations With No Effect on Uric Acid Metabolism, Cytochrome P-450 SubstratesProducts: KOLSIN 0.5 MG FİLM KAPLI TABLET,60 ADET, COLCHICUM DISPERT 0,5 MG FILM TABLET, 50 ADETHepatitis B Vaccine (Recombinant)
go.drugbank.com/drugs/DB11627ApprovedInvestigationalWithdrawnIn Canada, the United States and Northern Europe, 4% to 6% of the population are infected during their lifetime (mostly young adults); between 5% and 10% of infections lead to persistent viremia (carrier … In Asia, infection often occurs early in life, leading to a hepatitis B marker prevalence of more than 70% in the general population and a carrier rate of up to 20%.
Mixtures: HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN FLAKON, 10 ADET, HEXAXIM 0.5 ML IM ENJEKSİYONLUK SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR, 10 ADETProducts: ENGERIX-B PEDIYATRIK 10 MCG/0,5 ML IM ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTOR, 50 DOZ, HBVAXPRO INJECTION 10 MCG/MLEnalapril
go.drugbank.com/drugs/DB00584ApprovedInvestigationalVet approvedUltimately, enalaprilat works to reduce blood pressure and blood fluid volume. … Enalapril is an orally-active and long-acting nonsulphydryl antihypertensive agent that suppresses the renin-angiotensin-aldosterone system to lower blood pressure.
Mixtures: ZANIPRESS 10 MG/10 MG FILM TABLET, 30 ADET, ZANIPRESS 10 MG/10 MG FILM TABLET, 90 ADETProducts: ENAPRIL-10 TABLET 10 mg, GLIOTEN 10 TABLET 10 mgFilgrastim
go.drugbank.com/drugs/DB00099ApprovedInvestigationalIt has an amino acid sequence identical to endogenous G-CSF, but it is non-glycosylated unlike the endogenous G-CSF and has an N-terminal methionine added in the sequence for expression in _E. Coli_. … Filgrastim mimics the biological actions of G-CSF to increase the levels of neutrophils in the blood.
Synonyms: Tbo-filgrastimProducts: NEUKINE 300 MCG/1.0 ML, NIVESTIM 30 MU/0,5 ML SC/IV ENJEKSIYONLUK ÇÖZELTI IÇEREN KULLANIMA HAZIR ENJEKTÖR, 10 ADETLatanoprost
go.drugbank.com/drugs/DB00654ApprovedInvestigationalLatanoprost is a prodrug analog of prostaglandin F2 alpha that is used to treat elevated intraocular pressure (IOP). It was initially approved by the FDA in 1998. … [A184493] It has been found to be well-tolerated and its use does not normally result in systemic adverse effects like other drugs used to treat elevated intraocular pressure, such as [Timolol].
Synonyms: propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate, isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoateMixtures: Xalacom 50 Mikrogramm/ml + 5 mg/ml Augentropfen, LatanoTim-Vision 50 Mikrogramm/ml + 5 mg/ml AugentropfenRiluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalRiluzole is marketed as Rilutek by Sanofi. … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: TEGLUTIK 5 MG/ ML ORAL SÜSPANSIYON, 300 ML, RILUTEK 50 MG