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Displaying results 7591 - 7600 of 9714 in total
  1. Drug

    Valrubicin

    go.drugbank.com/drugs/DB00385
    Approved

    Valrubicin (N-trifluoroacetyladriamycin-14-valerate) is a chemotherapy drug commonly marketed under the trade name VALSTAR. … It is a semisynthetic analog of the [doxorubicin], which is an anthracycline drug. Used in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.

    Synonyms: (8S, 10S)-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-10-[[2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione 8²-valerate
  2. Drug

    Hyoscyamine

    go.drugbank.com/drugs/DB00424
    ApprovedInvestigational

    [A228713] Hyoscyamine is used for a wide variety of treatments and therapeutics due to its antimuscarinic properties. … Hyoscyamine is a tropane alkaloid and the levo-isomer of [atropine].[A228423] It is commonly extracted from plants in the _Solanaceae_ or nightshade family.

    Synonyms: L-Hyoscyamine, L-Tropine tropateMixtures: Uro-L
  3. Drug

    Streptozocin

    go.drugbank.com/drugs/DB00428
    ApprovedInvestigational

    An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

  4. Drug

    Pefloxacin

    go.drugbank.com/drugs/DB00487
    Approved

    A synthetic broad-spectrum fluoroquinolone antibacterial agent active against most gram-negative and gram-positive bacteria.

  5. Drug

    Gadoversetamide

    go.drugbank.com/drugs/DB00538
    Approved

    Gadoversetamide, marketed under the trade name OptiMARK, is a gadolinium compound used as a contrast agent in magnetic resonance imaging (MRI), particularly imaging of the brain, spine and liver.

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Docosanol

    go.drugbank.com/drugs/DB00632
    Approved

    Docosanol is a drug used for topical treatment for recurrent herpes simplex labialis episodes (episodes of cold sores or fever blisters). … A saturated 22-carbon aliphatic alcohol, docosanol exhibits antiviral activity against many lipid enveloped viruses including herpes simplex virus (HSV).

  7. Drug

    Pemetrexed

    go.drugbank.com/drugs/DB00642
    ApprovedInvestigational

    Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta.

    Categories: OAT3/SLC22A8 Substrates with a Narrow Therapeutic Index, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexProducts: NEXTREXED 500 MG POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE, PEMETREXED MASTERS® 500 MG POLVO LIOFILIZADO ESTÉRIL PARA RECONSTITUIR A SOLUCION INYECTABLE.
  8. Drug

    Leucovorin

    go.drugbank.com/drugs/DB00650
    ApprovedInvestigational

    Leucovorin, also known as folinic acid or citrovorum factor, is a reduced form of folic acid that serves as a vital coenzyme in nucleic acid synthesis. … [L56091, L56092] Historically developed in 1945, leucovorin has long been a staple on the World Health Organization’s List of Essential Medicines.

    Synonyms: L(-)-5-Formyl-5,6,7,8-tetrahydrofolic acid, 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acidCategories: Compounds used in a research, industrial, or household setting
  9. Drug

    Cephaloglycin

    go.drugbank.com/drugs/DB00689
    Approved

    A cephalorsporin antibiotic that is no longer commonly used.

  10. Drug

    Ergotamine

    go.drugbank.com/drugs/DB00696
    Approved

    A vasoconstrictor found in ergot of Central Europe. It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index