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Velufenacin
go.drugbank.com/drugs/DB21473InvestigationalVelufenacin is under investigation in clinical trial NCT05282069 (A Study to Evaluate the Efficacy and Safety of DA-8010 in Patients With Overactive Bladder). … The usage of the INN stem '-fenacin' in the name indicates that Velufenacin is a muscarinic receptor antagonist.
Lepzacitinib
go.drugbank.com/drugs/DB21646InvestigationalLepzacitinib is under investigation in clinical trial NCT05432596 (Study of ATI-1777 in Patients 12 to 65 Years Old With Mild to Severe Atopic Dermatitis). … The usage of the INN stem '-citinib' in the name indicates that Lepzacitinib is a Janus kinase inhibitor.
Luvometinib
go.drugbank.com/drugs/DB21696InvestigationalLuvometinib is under investigation in clinical trial NCT07004075 (FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF Alteration). … The usage of the INN stem '-tinib' in the name indicates that Luvometinib is a tyrosine kinase inhibitor.
Pebezertinib
go.drugbank.com/drugs/DB21705InvestigationalPebezertinib is under investigation in clinical trial NCT05241873 ((Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations). … The usage of the INN stem '-ertinib' in the name indicates that Pebezertinib is a epidermal growth factor receptor (EGFR) inhibitor.
SB 11285
go.drugbank.com/drugs/DB17511Investigational[L45123] SB 11285 is under investigation in clinical trial NCT04096638 (Evaluating Safety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid Tumors).
FF-10501-01
go.drugbank.com/drugs/DB17554Investigational[A257306] FF-10501-01 is under investigation in clinical trial NCT03486353 (A Study of FF-10501-01 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome).
Dihydroxyacetone
go.drugbank.com/drugs/DB01775ExperimentalIt is readily phosphorylated to dihydroxyacetone phosphate by triokinase in erythrocytes. In combination with naphthoquinones it acts as a sunscreening agent. [PubChem] … Its addition to blood preservation solutions results in better maintenance of 2,3-diphosphoglycerate levels during storage.
Pirmitegravir
go.drugbank.com/drugs/DB18974InvestigationalPirmitegravir is under investigation in clinical trial NCT05869643 (A Clinical Trial of STP0404 in Treatment-naïve Adults With HIV-1 Infection).
Pegtarviliase
go.drugbank.com/drugs/DB18999InvestigationalPegtarviliase is under investigation in clinical trial NCT05154890 (A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency).
BMS-741672
go.drugbank.com/drugs/DB19004InvestigationalBMS-741672 is under investigation in clinical trial NCT00699790 (Proof of Confidence Study of CCR2 Antagonist (BMS-741672) in Insulin Resistance).
Synonyms: N-(5-(ISOPROPYL(METHYL)AMINO)-2-(2-OXO-3-((6-(TRIFLUOROMETHYL)QUINAZOLIN-4-YL)AMINO)PYRROLIDIN-1-YL)CYCLOHEXYL)METHANESULFONAMIDE