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AGTC-402
go.drugbank.com/drugs/DB18433InvestigationalAGTC-402 is a recombinant adeno-associated virus vector expressing the cyclic nucleotide gated channel alpha subunit (CNGA3).
Synonyms: rAAV2tYF-PR.1-hCNGA3BJ-001
go.drugbank.com/drugs/DB18585InvestigationalBJ-001 is a recombinant human interleukin-15/IL-15 receptor alpha complex with linked integrin-binding motif.
ECT204
go.drugbank.com/drugs/DB18605InvestigationalECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.
SLN500
go.drugbank.com/drugs/DB18636ExperimentalSLN500 is a synthetic double-strand small interfering ribonucleic acid (siRNA) oligonucleotide drug directed against C3 messenger RNA
Prosetin
go.drugbank.com/drugs/DB18649InvestigationalProsetin is an orally administered blocker of MAP4K under investigation for the treatment of amyotrophic lateral sclerosis.[L48360]
Rovaleucel
go.drugbank.com/drugs/DB18691InvestigationalRovaleucel is an EBV-specific autologous T-cell therapy under investigation for the treatment of EBV-positive cancers.
RWJ-800088
go.drugbank.com/drugs/DB18693InvestigationalRWJ-800088 is a synthetic PEGylated thrombopoietin (TPO) mimetic (TPOm) peptide with no sequence homology to endogenous TPO.
Synonyms: -GLUTAMYLGLYCYL-L-PROLYL-L-THREONYL-L-LEUCYL-L-ARGINYL-L-GLUTAMINYL-3-(2-NAPHTHALENYL)-L-ALANYL-L-LEUCYL-L-ALANYL-L-ALANY, METHOXYPOLYETHYLENEGLYCOL20000-PROPIONYL-L-ISOLEUCYL-L-GLUTAMYL-GLYCYL-L-PROLYL-L-THREONYL-L-LEUCYL-L-ARGINYL-L-GLUTAMINYL-L-2-NAPHTHYLALANYL-L-LEUCYL-L-ALANYL-L-ALANYL-L-ARGINYLSARCOSYL-NE-(METHOXYPOLYETHYLENEGLYCOL20000ASTX-029
go.drugbank.com/drugs/DB18900InvestigationalASTX-029 is under investigation in clinical trial NCT03520075 (Study of ASTX029 in Subjects With Advanced Solid Tumors).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2H-ISOINDOLE-2-ACETAMIDE, 6-(5-CHLORO-2-((TETRAHYDRO-2H-PYRAN-4-YL)AMINO)-4-PYRIMIDINYL)-N-((1S)-1-(3-FLUORO-5-METHOXYPHENYL)-2-HYDROXYETHYL)-1,3-DIHYDRO-.ALPHA.-METHYL-1-OXO-, (.ALPHA.R)-Tamnorzatinib
go.drugbank.com/drugs/DB19201InvestigationalTamnorzatinib is under investigation in clinical trial NCT03176277 (A Study of ONO-7475 in Patients With Acute Leukemias).
Synonyms: 3-quinolinecarboxamide, n-(5-((6,7-dimethoxy-4-quinolinyl)oxy)-2-pyridinyl)-1,2,5,6,7,8-hexahydro-2,5-dioxo-1-phenyl-, N-(5-((6,7-dimethoxyquinolin-4-yl)oxy)pyridin-2-yl)-2,5-dioxo-1-phenyl-1,2,5,6,7,8-hexahydroquinoline-3-carboxamideAbiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: (115-212), hinge 1-12 S10>P (222) (213-224), CH2 L, Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1