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Tretamine
go.drugbank.com/drugs/DB14031ExperimentalToxic alkylating agent used in industry; also as antineoplastic and research tool to produce chromosome aberrations and cancers.
Synonyms: TEMAgerafenib
go.drugbank.com/drugs/DB15068InvestigationalAgerafenib is under investigation in clinical trial NCT03052569 (Expanded Access to RXDX-105 for Cancers With RET Alterations).
anti-OX40 antibody BMS 986178
go.drugbank.com/drugs/DB15773InvestigationalA macrocyclic peptide (BMS-986189) with activity in binding and functional assays comparable to a PD-L1 antibody.
Izencitinib
go.drugbank.com/drugs/DB16660InvestigationalIzencitinib is under investigation in clinical trial NCT03920254 (TD-1473 Long-term Safety (LTS) Ulcerative Colitis (UC) Study).
Trotabresib
go.drugbank.com/drugs/DB17421InvestigationalTrotabresib is an oral, potent, and reversible inhibitor of the epigenetic target bromodomain and extra-terminal (BET) proteins.
OPC1
go.drugbank.com/drugs/DB17944ExperimentalOPC1 is an oligodendrocyte progenitor cell therapy being investigated for the treatment of acute spinal cord injury.[L47082]
PMC-403
go.drugbank.com/drugs/DB18132InvestigationalPMC-403 is a novel Tie2-activating antibody being investigated for the treatment of systemic capillary leak syndrome.
Synonyms: a fully human monoclonal antibody that binds and activates the Tie2 receptorNGN-101
go.drugbank.com/drugs/DB18335InvestigationalNGN-101 is an adeno-associated virus serotype 9 vector with engineered transgene encoding the human CLN5 gene
AGTC-402
go.drugbank.com/drugs/DB18433InvestigationalAGTC-402 is a recombinant adeno-associated virus vector expressing the cyclic nucleotide gated channel alpha subunit (CNGA3).
ECT204
go.drugbank.com/drugs/DB18605InvestigationalECT204 is an autologous T-cell therapy whereby T cells are genetically modified to target tumor-specific antigens.