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Tretinoin
go.drugbank.com/drugs/DB00755ApprovedInvestigationalNutraceutical[A257689] In human circulation, tretinoin is normally found at very low concentrations, approximately 4 to 14 nmol/L. … Tretinoin, also known as all-trans-retinoic acid (ATRA), is a naturally occurring derivative of [vitamin A] (retinol).
Synonyms: Tretin M, Vitamin A acidInternational brands: Stieva-ASevelamer
go.drugbank.com/drugs/DB00658ApprovedInvestigationalSevelamer is a phosphate binding drug used to prevent hyperphosphataemia in patients with chronic renal failure. It is marketed by Genzyme under the trade name Renagel.
Categories: Compounds used in a research, industrial, or household setting, Drugs for Treatment of Hyperkalemia and HyperphosphatemiaProducts: RIFOSAR-POS, RENADIN 800 MG FILM TABLET, 180 ADETDermatophagoides farinae
go.drugbank.com/drugs/DB10400ApprovedInvestigationalThis combination is approved for as a year-round, once-a-day tablet that's dissolved under the tongue as a treatment for dust mite allergies. … Dermatophagoides farinae extracts are sterile solutions used for intradermal testing or subcutaneous immunotherapy.
Mixtures: Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 10000 AU per mL, Standardized Mite Mix, Dermatophagoides pteronyssinus and Dermatophagoides farinae, 30000 AU per mLProducts: Standardized Mite, Dermatophagoides farinae, Intradermal, 30 AU per mL, Standardized Mite, Dermatophagoides farinae, Scratch or Bulk, 30000 AU per mLHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigational[L14312]** Hydroxychloroquine was granted FDA approval on 18 April 1955.[L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546] … [A192132] **The FDA emergency use authorization for hydroxychloroquine and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020.
Synonyms: 7-chloro-4-(4-(ethyl(2-hydroxyethyl)amino)-1-methylbutylamino)quinoline, 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinolineProducts: Pro-hydroxyquine - 200, HALOXIN TABLET 100 mgOlaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigational[L41100, L40908, L43792] PARP inhibitors represent a novel class of anti-cancer therapy and they work by taking advantage of a defect in DNA repair in cancer cells with BRCA mutations and inducing cell … Olaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2.
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingSynonyms: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-oneGlatiramer
go.drugbank.com/drugs/DB05259ApprovedInvestigational[A248870] Along with [human interferon beta], [teriflunomide], and [dimethyl fumarate], glatiramer acetate is a first-line drug for patients with MS. … encephalitis (MS animal model).
Synonyms: (T,G)-A-L, COP 1Products: GLATIR® 40 MG/ML, โคแพคซอน (20 MG/ML)Tetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnThe FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … Tetracycline is a broad spectrum polyketide antibiotic produced by the Streptomyces genus of Actinobacteria.
Mixtures: Pylera 140 mg/125 mg/125 mg Hartkapseln, Pylera 140 mg/125 mg/125 mg HartkapselnCategories: Antibiotics for Topical Use, Antibacterials for Systemic UseRamucirumab
go.drugbank.com/drugs/DB05578ApprovedInvestigationalRamucirumab is indicated for us in advanced gastric or gastro-esophageal junction adenocarcinoma as a single agent or in combination with paclitaxel after prior fluoropyrimidine- or platinum-containing … VEGFR stimulation also mediates downstream signalling required for angiogenesis and is postulated to be heavily involved in cancer progression, making it a highly likely drug target.
Products: CYRAMZA 500 MG/50 ML İNFÜZYONLUK ÇÖZELTİ KONSANTRESİ İÇEREN FLAKON, 1 ADET, CYRAMZA 100MG/10 ML INFÜZYONLUK ÇÖZELTI KONSANTRESI IÇEREN FLAKON, 1 ADETEcallantide
go.drugbank.com/drugs/DB05311ApprovedEcallantide is a recombinant 60-amino-acid protein produced in _Pichia pastoris_ yeast cells that contains three intramolecular disulfide bonds [FDA Label]. … Ecallantide is a potent and selective human plasma kallikrein inhibitor that is indicated for the symptomatic treatment of hereditary angioedema.
Products: KALBITOR® 10 MG / MLFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalFlunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenylprop-2-en-1-yl]piperazine