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Displaying results 7791 - 7800 of 10000 in total
  1. Drug

    ZD4407

    go.drugbank.com/drugs/DB06539
    Experimental

    The drug ZD4407, an antiasthmatic developed by AstraZeneca, functions as a 5-lipoxygenase inhibitor. … It entered Phase 1 clinical trials for chronic obstructive pulmonary disease (COPD) in the United Kingdom but was discontinued during this phase in March 2003

    Synonyms: 1,3-DIHYDRO-1-METHYL-5-((4-((2S,4R)-TETRAHYDRO-4-HYDROXY-2-METHYL-2H-PYRAN-4-YL)-2-THIENYL)THIO)-2H-INDOL-2-ONE, 5-(4-((2S,4R)-4-HYDROXY-2-METHYLOXAN-4-YL)THIOPHEN-2-YL)SULFANYL-1-METHYL-3H-INDOL-2-ONE
  2. Drug

    TM5614

    go.drugbank.com/drugs/DB16516
    Investigational

    TM5614 inhibition of PAI-1, specifically, downregulates PCSK9 at the transcriptional level[A228793]. … TM5614 is a novel, orally active, plasminogen activator inhibitor 1 (PAI-1) inhibitor[A228788,A228793,].

  3. Drug

    TZ-101

    go.drugbank.com/drugs/DB18690
    Experimental

    TZ-101 composes of [GDP-L-fucose] and fucosyltransferase VI

  4. Drug

    AZD-7295

    go.drugbank.com/drugs/DB12724
    Investigational

    AZD7295 has been investigated for the treatment of Hepatitis C.

  5. Drug

    Glyceryl Trioleate

    go.drugbank.com/drugs/DB13038
    Investigational

    Glyceryl Trioleate has been investigated for the treatment of Adrenoleukodystrophy.

  6. Drug

    Surinabant

    go.drugbank.com/drugs/DB13070
    Investigational

    Surinabant has been investigated for the treatment of Smoking Cessation.

    Categories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Gisadenafil

    go.drugbank.com/drugs/DB11902
    Investigational

    Gisadenafil has been investigated for the treatment of Prostatic Hyperplasia.

    Categories: Heterocyclic Compounds, 1-Ring, Cyclic Nucleotide Phosphodiesterases, Type 5
  8. Drug

    Napabucasin

    go.drugbank.com/drugs/DB12155
    Investigational

    Napabucasin has been investigated for the treatment of Colorectal Carcinoma.

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Puerarin

    go.drugbank.com/drugs/DB12290
    Investigational

    Puerarin has been investigated for the treatment of Alcohol Abuse.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  10. Drug

    Piclozotan

    go.drugbank.com/drugs/DB12361
    Investigational

    Piclozotan has been investigated for the treatment of Parkinson's Disease.

    Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor Agonists