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Luxdegalutamide
go.drugbank.com/drugs/DB22370InvestigationalJSB462 is under investigation in clinical trial NCT07047118 (A Study of JSB462 (Luxdegalutamide) Plus Lutetium (177Lu) Vipivotide Tetraxetan in Patients With Metastatic Castration Resistant Prostate Cancer
Izalontamab brengitecan
go.drugbank.com/drugs/DB22567InvestigationalIzalontamab brengitecan is under investigation in clinical trial NCT07054567 (A Study of BL-B01D1 + Pembrolizumab ± Bevacizumab in Patients With Recurrent or Metastatic Cervical Cancer and Endometrial
ATORM-C
go.drugbank.com/drugs/DB33983ExperimentalATORM-C is under investigation in clinical trial NCT07822087 (A Phase 1 Study of ATORM-C in Patients With Crohn's Disease).
MYR-101
go.drugbank.com/drugs/DB17075InvestigationalASPA is produced in oligodendrocytes, and participates in the metabolism of N-acetylaspartate (NAA). … Canavan disease is a fatal childhood genetic disorder characterized by white matter degeneration in the brain.
Imdusiran
go.drugbank.com/drugs/DB19014InvestigationalImdusiran is under investigation in clinical trial NCT06245291 (Study of Imdusiran (AB-729) in Combination With Intermittent Dosing of Durvalumab in Subjects With Chronic HBV Infection).
Magrolimab
go.drugbank.com/drugs/DB16225InvestigationalMagrolimab is under investigation in clinical trial NCT02953782 (Trial of Magrolimab (Hu5f9-g4) in Combination With Cetuximab in Participants With Solid Tumors and Advanced Colorectal Cancer).
Letaplimab
go.drugbank.com/drugs/DB16679InvestigationalLetaplimab is under investigation in clinical trial NCT04485052 (Efficacy and Safety Evaluation of IBI188 in Combination With Azacitidine in Treatment of Patients With Acute Myeloid Leukemia).
Vorsetuzumab mafodotin
go.drugbank.com/drugs/DB15352InvestigationalVorsetuzumab mafodotin is under investigation in clinical trial NCT01677390 (A Phase 1b Study of SGN-75 in Combination With Everolimus in Patients With Renal Cell Carcinoma).
Theanine
go.drugbank.com/drugs/DB12444InvestigationalTheanine, a precursor of ethylamine, is found in green tea. It is under investigation in clinical trial NCT00291070 (Effects of L-Theanine in Boys With ADHD).
Synonyms: N-ethyl-L-glutamine, N(5)-ethyl-L-glutamineMelarsomine
go.drugbank.com/drugs/DB11528ExperimentalVet approvedIt is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection.