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Radiprodil
go.drugbank.com/drugs/DB12260InvestigationalRadiprodil has been used in trials studying the treatment of Infantile Spasms (IS) and Diabetic Peripheral Neuropathic Pain.
Categories: Heterocyclic Compounds, 1-RingAvoplacel
go.drugbank.com/drugs/DB18659InvestigationalAvoplacel (PLX-R18) is an allogeneic cell therapy under investigation for the treatment of acute radiation syndrome.[L48370]
Synonyms: Ex-vivo expanded placental adherent stromal cellsVenanprubart
go.drugbank.com/drugs/DB18891InvestigationalVenanprubart is under investigation in clinical trial NCT05781451 (Anti-btla Agonist Therapy in Subjects With Primary Sjogren's Syndrome).
BMS-770767
go.drugbank.com/drugs/DB18902InvestigationalBMS-770767 is under investigation in clinical trial NCT01058083 (Safety Study of BMS-770767 in Subjects With Hypercholesterolemia).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-(8-(2-CHLOROPHENOXY)(1,2,4)TRIAZOLO(4,3-A)PYRIDIN-3-YL)BICYCLO(2.2.1)HEPTAN-1-OL, BICYCLO(2.2.1)HEPTAN-1-OL, 4-(8-(2-CHLOROPHENOXY)-1,2,4-TRIAZOLO(4,3-A)PYRIDIN-3-YL)-Edecesertib
go.drugbank.com/drugs/DB18917InvestigationalEdecesertib is under investigation in clinical trial NCT05629208 (Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)).
Synonyms: 3-Pyridinecarboxamide, 4-[[(1R)-1-cyanoethyl]amino]-6-(3-cyanopyrrolo[1,2-b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3-methylbutyl]-, 4-{[(1R)-1-cyanoethyl]amino}-6-(3-cyanopyrrolo[1,2- b]pyridazin-7-yl)-N-[(2R)-2-fluoro-3-hydroxy-3- methylbutyl]pyridine-3-carboxamideNelmastobart
go.drugbank.com/drugs/DB19000InvestigationalNelmastobart is under investigation in clinical trial NCT05990543 (Combination of Nelmastobart and Capecitabine Therapy in Metastatic Colorectal Cancer).
Atamparib
go.drugbank.com/drugs/DB19028InvestigationalAtamparib is under investigation in clinical trial NCT05127590 (RBN-2397 in Combination With Pembrolizumab in Patients With SCCL).
Synonyms: 3(2h)-pyridazinone, 5-(((1s)-1-methyl-2-(3-oxo-3-(4-(5-(trifluoromethyl)-2-pyrimidinyl)-1-piperazinyl)propoxy)ethyl)amino)-4-(trifluoromethyl)-, 5-(((2s)-1-(3-oxo-3-(4-(5-(trifluoromethyl)pyrimidin-2- yl)piperazin-1-yl)propoxy)propan-2-yl)amino)-4- (trifluoromethyl)pyridazin-3(2h)-oneElimusertib
go.drugbank.com/drugs/DB19041InvestigationalElimusertib is under investigation in clinical trial NCT05071209 (Elimusertib for the Treatment of Relapsed or Refractory Solid Tumors).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1,7-naphthyridine, 2-((3r)-3-methyl-4-morpholinyl)-4-(1-methyl-1h-pyrazol-5-yl)-8-(1h-pyrazol-3-yl)-Gamma cyclodextrin
go.drugbank.com/drugs/DB19173InvestigationalGamma cyclodextrin is under investigation in clinical trial NCT03931057 (The use of ADV6209 for Premedication in Pediatric Anesthesia).
Synonyms: Cyclooctakis-(1->4)-(.alpha.-d-glucopyranosyl), Ringdex cSolrikitug
go.drugbank.com/drugs/DB19301InvestigationalSolrikitug is under investigation in clinical trial NCT06496607 (A Study to Evaluate Solriktug in Adult Participants With Asthma).
Synonyms: Immunoglobulin G1-kappa, anti-[Homo sapiens CRLF2 (cytokine receptor like factor 2,TSLP, thymic stromal lymphopoietin)], humanized monoclonal antibody