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Displaying results 7861 - 7870 of 10000 in total
  1. Drug

    Pemtumomab

    go.drugbank.com/drugs/DB18563
    Experimental

    Pemtumomab is a murine monoclonal antibody radiolabeled with Yttrium-90. It targets the mucin 1 (MUC1) protein.

    Synonyms: Murine MAb to polymorphic epithelial mucin, human milk fat globule 1
  2. Drug

    PA3-17

    go.drugbank.com/drugs/DB18569
    Investigational

    PA3-17 is CD7-directed chimeric antigen receptor (CAR) T-cell therapy.

    Synonyms: Chimeric Antigen Receptor T Cells targeting CD7
  3. Drug

    BEA-17

    go.drugbank.com/drugs/DB18574
    Experimental

    BEA-17 is a small molecule targeted degrader of the epigenetic enzyme LSD1 and its co-factor CoREST.[L48330] It is under investigation for the treatment of glioblastoma.

  4. Drug

    SPL84-23-1

    go.drugbank.com/drugs/DB18575
    Experimental

    5'-5MeC-5MeU-G-5MeC-A-A-5MeC-A-G-A-5MeU-G-G-A-A-G-A-5MeC-5MeU-3' … SPL84-23-1 is a sodium salt of 19-bp single-stranded RNA uniformly modified 2'-O-(2-methoxyethyl) phosphorothioate Antisense Oligonucleotide (ASO) consisting of 19 nucleotide residues with the sequence

  5. Drug

    TRK-001

    go.drugbank.com/drugs/DB18577
    Investigational

    TRK-001 is an autologous regulatory T-cell therapy. It is being investigated for the prevention of graft rejection following solid organ transplantation.

    Synonyms: Natural Regulatory T Cells (T-Regs), Expanded with Interleukin-2, ExpAct Beads (CD3/CD28; Miltenyi), Rapamycin and Transforming Growth Factor-beta
  6. Drug

    ETX101

    go.drugbank.com/drugs/DB18579
    Investigational

    ETX101 is a non-replicating recombinant adeno associated viral vector, serotype 9, designed to promote increased transcription of SCN1A gene.

    Synonyms: non-replicating recombinant adeno associated viral vector, serotype 9, designed to promote increased transcription of SCN1A gene
  7. Drug

    PBFT02

    go.drugbank.com/drugs/DB18580
    Investigational

    PBFT02 is a non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein progranulin.

    Synonyms: Non-replicating recombinant adeno-associated virus serotype 1 vector delivering human GRN gene encoding the protein progranulin
  8. Drug

    scAAV9.U7.ACCA

    go.drugbank.com/drugs/DB18582
    Investigational

    scAAV9.U7.ACCA is a non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding … Developed by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.

    Synonyms: non-replicating recombinant adeno-associated virus vector containing 4 antisense sequences designed to target exon 2 in the human DMD gene under the control of U7 small nuclear non-coding RNA
  9. Drug

    CSIC002

    go.drugbank.com/drugs/DB18584
    Experimental

    CSIC002 is a small-molecule Sema-3A inhibitor. It is being investigated for the treatment of anterior ischemic optic neuropathy.

  10. Drug

    NGN-401

    go.drugbank.com/drugs/DB18594
    Investigational

    NGN-401 is a recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding … protein 2 (MECP2).

    Synonyms: Recombinant serotype 9 adeno-associated virus (AAV) encoding an intron encoding a miRNA generating sequence, complementary miRNA binding sites and a full-length human methyl cytosine binding protein 2