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Quisovalimab
go.drugbank.com/drugs/DB16482InvestigationalCategories: Experimental Unapproved Treatments for COVID-19Novaferon
go.drugbank.com/drugs/DB16483InvestigationalCategories: Experimental Unapproved Treatments for COVID-19Chikungunya virus Senegal strain 37997 envelope protein E1
go.drugbank.com/drugs/DB21767ApprovedInvestigationalOne of three components of a recombinant Chikungunya virus vaccine called Vimkunya.
Debamestrocel
go.drugbank.com/drugs/DB17934InvestigationalDebamestrocel is under clinical development by BrainStorm Cell Therapeutics and is being investigated for the treatment of Amyotrophic Lateral Sclerosis (ALS).[L47266]
Navocaftor
go.drugbank.com/drugs/DB19039InvestigationalNavocaftor is under investigation in clinical trial NCT04853368 (Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/navocaftor/abbv-119 or Galicaftor/navocaftor … /abbv-576 Combination Therapies in Adult Participants With Cystic Fibrosis).
L523S
go.drugbank.com/drugs/DB06498InvestigationalAccording to Nemunaitis J., et al, "L523S is an immunogenic lung cancer antigen that has demonstrated preclinical safety when the gene is injected intramuscularly as an expressive plasmid (pVAX/L523S) … [A175909] It has been investigated as a lung cancer vaccine.
Amitriptylinoxide
go.drugbank.com/drugs/DB13114ApprovedWithdrawnAmitriptylinoxide has been used in trials studying Major Depression.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeAptazapine
go.drugbank.com/drugs/DB09305ExperimentalIt antagonised α2 adrenergic receptors approximately 10 times more effectively than mianserin, antagonised 5-HT2 receptors, agonised H1 receptors, and did not affect reuptake of serotonin or norepinephrine … Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity.
Tenitramine
go.drugbank.com/drugs/DB13637ExperimentalCategories: Vasodilators Used in Cardiac Diseases