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Displaying results 781 - 790 of 10000 in total
  1. Drug

    5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB08741
    Experimental

    Synonyms: 5-[[(2R)-2-cyclopropyl-7,8-dimethoxy-2H-chromen-5-yl]methyl]pyrimidine-2,4-diamine
  2. Drug

    4-Bromo-3-(5'-Carboxy-4'-Chloro-2'-Fluorophenyl)-1-Methyl-5-Trifluoromethyl-Pyrazol

    go.drugbank.com/drugs/DB03272
    Experimental

    Synonyms: 4-Bromo-3-(5'-Carboxy-4'-Chloro-2'-Fluorophenyl)-1-Methyl-5-Trifluoromethyl-Pyrazol
  3. Drug

    4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE

    go.drugbank.com/drugs/DB07531
    Experimental

    Synonyms: 4-{5-[(Z)-(2,4-DIOXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}BENZENESULFONAMIDE
  4. Drug

    Eluxadoline

    go.drugbank.com/drugs/DB09272
    ApprovedInvestigational

    Eluxadoline is a mixed mu-opioid receptor agonist, kappa-opioid receptor agonist, and a-delta opioid receptor antagonist indicated for use in diarrhea-predominant irritable bowel syndrome (IBS-D). … The mu-, kappa-, and delta-opioid receptors mediate endogenous and exogenous opioid response in the central nervous system and peripherally in the gastrointestinal system.

    Synonyms: 5-({(4-carbamoyl-2,6-dimethyl-L-phenylalanyl)[(1S)-1-(4-phenyl-1H-imidazol-2-yl)ethyl]amino}methyl)-2-methoxybenzoic acidCategories: Heterocyclic Compounds, 1-Ring, mu-Opioid Receptor Agonist
  5. Drug

    (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide

    go.drugbank.com/drugs/DB03690
    Experimental

    Synonyms: (Z,Z)-4-Hydroxy-N,N,N-Trimethyl-10-Oxo-7-[(1-Oxo-9-Octadecenyl)Oxy]-3,5,9-Trioxa-4-Phosphaheptacos-18-En-1-Aminium-4-Oxide
  6. Drug

    SB-409513

    go.drugbank.com/drugs/DB01793
    Experimental

    Synonyms: I-5
  7. Drug

    Defactinib

    go.drugbank.com/drugs/DB12282
    ApprovedInvestigational

    Defactinib is a small molecule kinase inhibitor targeted against focal adhesion kinase (FAK) and proline-rich tyrosine kinase-2 (Pyk2), the two members of the FAK family of nonreceptor tyrosine kinases … [L53198,L53208] FAK is important for the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, and its upregulation is a key

    Synonyms: N-methyl-4-[[4-[[3-[methyl(methylsulfonyl)amino]pyrazin-2-yl]methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]benzamideCategories: Heterocyclic Compounds, 1-Ring, Focal Adhesion Kinase 1, antagonists & inhibitors
  8. Drug

    Tiliquinol

    go.drugbank.com/drugs/DB20266
    Experimental

    Tiliquinol is a small molecule drug. Tiliquinol has a monoisotopic molecular weight of 159.07 Da.

    Categories: Heterocyclic Compounds, 2-Ring, tilbroquinol and tiliquinolSynonyms: 5-methyl-8-quinolinol, 5-methylquinolin-8-ol
  9. Drug

    Vitamin B 12 factor IIIm

    go.drugbank.com/drugs/DB02667
    Experimental

    Synonyms: Vitamin B 12 factor IIIm, 5-Methoxybenzimidazole vitamin B12
  10. Drug

    3-{[(2,2-dioxido-1,3-dihydro-2-benzothien-5-yl)amino]methylene}-5-(1,3-oxazol-5-yl)-1,3-dihydro-2H-indol-2-one

    go.drugbank.com/drugs/DB08124
    Experimental

    Synonyms: 3-{[(2,2-dioxido-1,3-dihydro-2-benzothien-5-yl)amino]methylene}-5-(1,3-oxazol-5-yl)-1,3-dihydro-2H-indol-2-one