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Displaying results 7891 - 7900 of 10000 in total
  1. Drug

    Lefradafiban

    go.drugbank.com/drugs/DB04863
    Investigational

    Lefradafiban is an oral platelet glycoprotein IIb/IIIa receptor antagonist being investigated in the treatment of angina.

  2. Drug

    Nisevokitug

    go.drugbank.com/drugs/DB17561
    Investigational

    and Efficacy of Novel Ruxolitinib Combinations in Myelofibrosis Patients). … Nisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety

    Categories: Amino Acids, Peptides, and Proteins
  3. Drug

    VSF-173

    go.drugbank.com/drugs/DB05753
    Investigational

    VSF-173 is an oral small molecule. It is an oral compound that has demonstrated effects on animal sleep/wake patterns and gene expression patterns suggestive of a stimulant effect. … It is developed for the treatment of excessive sleepiness. Study shows that VSF-173 possesses a novel mechanism to address disorders of excessive sleepiness.

  4. Drug

    Ombrabulin

    go.drugbank.com/drugs/DB12882
    Investigational

    Ombrabulin has been used in trials studying the treatment of Sarcoma, Neoplasms, Solid Tumor, Neoplasms, Malignant, and Advanced Solid Tumors, among others.

    Categories: Amino Acids, Peptides, and Proteins
  5. Drug

    Theralizumab

    go.drugbank.com/drugs/DB15717
    Investigational

    Theralizumab is a humanized anti-CD28 monoclonal antibody designed for treating autoimmune diseases and cancer. … After the first human trial, it was withdrawn due to severe toxicity (likely due to lymphopenia and human cytokine release).[A216527,A216532]

    Categories: Amino Acids, Peptides, and Proteins
  6. Drug

    Synephrine

    go.drugbank.com/drugs/DB09203
    Investigational

    While the compounds share some chemical and pharmacological similarities, they are in fact distinct chemical entities. … It is present in approved drug products as neo-synephrine, its m-substituted analog. p-synephrine and m-synephrine are known for their longer acting adrenergic effects compared to norepinephrine.

    Categories: Adrenergic and Dopaminergic Agents, Decongestants and Antiallergics
  7. Drug

    Alifedrine

    go.drugbank.com/drugs/DB20853
    Experimental

    Alifedrine is a small molecule drug. The usage of the INN stem '-drine' in the name indicates that Alifedrine is a sympathomimetic. Alifedrine has a monoisotopic molecular weight of 289.2 Da.

    Categories: Compounds used in a research, industrial, or household setting
  8. Indication

    Liver Cancer

    go.drugbank.com/conditions/DBCOND0028488
    Drugs: Uracil
    Synonyms: CA - Liver cancer
  9. Drug

    Pivagabine

    go.drugbank.com/drugs/DB12951
    Investigational

    Pivagabine has been used in trials studying the treatment of Stress and Anxiety.

    Categories: Amino Acids, Peptides, and Proteins
  10. Drug

    Olpasiran

    go.drugbank.com/drugs/DB19001
    Investigational

    Olpasiran is under investigation in clinical trial NCT05581303 (Olpasiran Trials of Cardiovascular Events and Lipoprotein(a) Reduction (Ocean(a)) - Outcomes Trial).

    Categories: Nucleic Acids, Nucleotides, and Nucleosides