Search

Displaying results 7891 - 7900 of 10000 in total
  1. Drug

    Neladalkib

    go.drugbank.com/drugs/DB21712
    Investigational

    Neladalkib is under investigation in clinical trial NCT06765109 (Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC). … Neladalkib is a small molecule drug. The usage of the INN stem '-alkib' in the name indicates that Neladalkib is a ALK (anaplastic lymphoma kinase) inhibitor.

    Synonyms: an orally bioavailable ALK inhibitor (a macrocyclic compound containing nitrogen heterocycles)
  2. Drug

    BBM-H803

    go.drugbank.com/drugs/DB17700
    Investigational

    BBM-H803 is a recombinant adeno-associated virus (AAV) based gene therapy drug for hemophilia A developed and manufactured by Belief BioMed. … It consists of an adeno-associated virus vector containing an expression cassette of the human Factor VIII transgene.

  3. Drug

    TNP-2092

    go.drugbank.com/drugs/DB16312
    Investigational

    TNP-2092 is under investigation in clinical trial NCT03964493 (TNP-2092 to Treat Acute Bacterial Skin and Skin Structure Infection).

    Categories: Heterocyclic Compounds with 4 or More Rings
  4. Drug

    TAS-102

    go.drugbank.com/drugs/DB08937
    Investigational

    TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. … It is composed of the thymidine phosphorylase inhibitor (TPI) tipiracil and the cytotoxin trifluridine. Trifluridine inhibits tumor growth by being incorporated into DNA during DNA synthesis.

  5. Drug

    Tolciclate

    go.drugbank.com/drugs/DB13360
    Experimental

    Categories: Antifungals for Topical Use, Antifungals for Dermatological Use
  6. Drug

    Relamorelin

    go.drugbank.com/drugs/DB12678
    Investigational

    Relamorelin has been investigated for the treatment and basic science of Gastroparesis, Gastric Motility, Diabetes Mellitus, Parkinson's Disease, and Chronic Constipation, among others.

  7. Target

    Folate receptor

    go.drugbank.com/bio_entities/BE0010260
    TransporterTargetHumans

    Has high affinity for folate and folic acid analogs at neutral pH. … Required for normal embryonic development and normal cell proliferation (By similarity)

    Synonyms: FOLR
  8. Drug

    TT 173

    go.drugbank.com/drugs/DB17717
    Investigational

    TT 173 is a Modified Human Tissue Factor currently being investigated to treat bleeding disorders such as hemophilia and von Willebrand disease, as well as bleeding episodes in cutaneous injuries or dental

  9. Drug

    Tengonermin

    go.drugbank.com/drugs/DB16689
    Investigational

    [A233270] A study also demonstrated that binding of the NGR-motif to CD13 determined both the homing of NGR-hTNF to tumor vessels and the increase in its antiangiogenic activity.[A233270] … [A233270] Literature demonstrates that NGR-peptides bind to a CD13 isoform, of which expression is restricted to tumor vasculature cells.

  10. Drug

    Taragarestrant

    go.drugbank.com/drugs/DB21574
    Investigational

    Taragarestrant is under investigation in clinical trial NCT06954961 (A Study to Evaluate D-0502 in Subjects With ER+ Her2- Locally Advanced or Metastatic Breast Cancer). … Taragarestrant is a small molecule drug.