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Displaying results 7941 - 7950 of 10000 in total
  1. Drug

    (S)-Warfarin

    go.drugbank.com/drugs/DB14055
    Investigational

    S-warfarin is 2-5 times more potent than the R-isomer in producing an anticoagulant response.[A7166] … Warfarin consists of a racemic mixture of two active enantiomers—R- and S- forms—each of which is cleared by different pathways.

  2. Drug

    Picafibrate

    go.drugbank.com/drugs/DB19574
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Picafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Picafibrate is a small molecule drug.

  3. Drug

    Tiafibrate

    go.drugbank.com/drugs/DB19874
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Tiafibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Tiafibrate is a small molecule drug.

  4. Drug

    Urefibrate

    go.drugbank.com/drugs/DB20849
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Urefibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Urefibrate is a small molecule drug.

  5. Drug

    Sitofibrate

    go.drugbank.com/drugs/DB21192
    Experimental

    The usage of the INN stem '-fibrate' in the name indicates that Sitofibrate is a clofibrate derivative, peroxisome proliferator activated receptor-a (PPAR-a) agonist. … Sitofibrate is a small molecule drug.

  6. Drug

    Zatonacaftor

    go.drugbank.com/drugs/DB21625
    Experimental

    The usage of the INN stem '-caftor' in the name indicates that Zatonacaftor is a Cystic fibrosis transmembrane regulator (CFTR) protein modulator, corrector, and amplifier. … Zatonacaftor is a small molecule drug.

  7. Drug

    Pegsitacianine

    go.drugbank.com/drugs/DB19098
    Investigational

    Pegsitacianine is under investigation in clinical trial NCT05576974 (A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence … Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)).

  8. Drug

    scyllo-inositol

    go.drugbank.com/drugs/DB03106
    Investigational

    An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction. Scyllitol has been investigated for the treatment of Alzheimer Disease.

  9. Drug

    Zilebesiran

    go.drugbank.com/drugs/DB18929
    Investigational

    Zilebesiran is under investigation in clinical trial NCT06272487 (Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care

  10. Drug

    Trigonellamide

    go.drugbank.com/drugs/DB11710
    Investigational

    Trigonellamide is under investigation in clinical trial NCT01930240 (The Safety of a Hypolipidemic Agent in Healthy Normal Volunteers).