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Etoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnEtoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inh...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridineDesipramine
go.drugbank.com/drugs/DB01151ApprovedDesipramine hydrochloride is a dibenzazepine-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-dep...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Novo-desipramine Fc - 50mg TabRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalRopinirole, also known as ReQuip, is a non-ergoline dopamine agonist used in Parkinson's disease and restless legs syndrome [FDA label], . It is manufactured by GlaxoSmithKline Pharmaceuticals. Ropinirole was initially approved in 1997 b...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: REQUIP PD 24 HOUR, REQUIP PD 24 HOUR 2mg Prolonged Release TabletsTiclopidine
go.drugbank.com/drugs/DB00208ApprovedTiclopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlo...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsProducts: Strokan FC Tablet 250mgAntihemophilic factor human
go.drugbank.com/drugs/DB13192ApprovedInvestigationalfusion protein which has an extended half-life compared with conventional factor VIII due to conjugation to the dimeric Fc domain of human immunoglobulin G1, a long-lived plasma protein [A31551]. … technology and is identical in sequence to endogenously produced Factor VIII, but does not contain the B-domain, which has no known biological function and [DB11607], which is a fully recombinant factor VIII-Fc
Mixtures: Monoclate-P, Humate-PSynonyms: F8 protein, humanEnsovibep
go.drugbank.com/drugs/DB19078InvestigationalEnsovibep is under investigation in clinical trial NCT04501978 (ACTIV-3: Therapeutics for Inpatients With COVID-19).
Synonyms: Designed ankyrin repeat protein (synthetic bivalent human albumin-binding) fusion protein with designed ankyrin repeat protein (synthetic trivalent severe acute respiratory syndrome coronavirus 2 spikePheniramine
go.drugbank.com/drugs/DB01620ApprovedPheniramine is a first-generation antihistamine in the alkylamine class, similar to brompheniramine and chlorpheniramine. It is used in some over-the-counter allergy as well as cold & flu products in combination with other drugs. Phe...
Mixtures: FAZOLIN F, SOLUTINA FProducts: FENİRAMİN-PF 45,5 MG/2 ML I.M./I.V. ENJEKSİYONLUK ÇÖZELTİ, 5 FLAKONErythropoietin
go.drugbank.com/drugs/DB00016ApprovedInvestigationalErythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. ...
Products: ERYPO FS 1000, ERYPO FS 2000Nicotinamide
go.drugbank.com/drugs/DB02701ApprovedInvestigationalAn important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent n...
Mixtures: BOTA C Reset, PNV 27-Ca/Fe/FACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsRAD 502
go.drugbank.com/drugs/DB17328ExperimentalSynonyms: Lutetium-177 labeled humanized monoclonal antibody targeting leucine rich repeat containing 15 (LRRC15)