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Displaying results 8001 - 8010 of 10000 in total
  1. Drug

    Romifidine

    go.drugbank.com/drugs/DB11543
    ExperimentalVet approved

    It is also used less commonly in a wide variety of other animal species. This drug's chemical structure closely resembles that of clonidine, however, romifidine is not approved for use in humans.

  2. Drug

    Devafidugene civaparvovec

    go.drugbank.com/drugs/DB16790
    Investigational

    It uses proprietary zinc finger nucleases (ZFN) that insert a functional copy of the alpha-L-iduronidase (IDUA) enzyme. … Developed by Sangamo Therapeutics, Inc., devafidugene civaparvovec is being investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46716]

  3. Drug

    CY-1503

    go.drugbank.com/drugs/DB17605
    Investigational

    It was investigated in cardiopulmonary bypass during surgical repair of congenital heart lesions. … CY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium salt, two beta-D-galactopyranosyl residues, one 2-acetamido-beta-Dglucopyranosyl unit, and one alpha-L-fucopyranosyl

  4. Drug

    SCIB1

    go.drugbank.com/drugs/DB18439
    Investigational

    It is being investigated for the treatment of melanoma. … It consists of plasmid DNA molecules that express a modified antibody in human cells, working to stimulate the patient's T cells to have a stronger reaction against melanoma cells.

  5. Drug

    Mitometh

    go.drugbank.com/drugs/DB12117
    Investigational

    Mitometh has been investigated for the treatment of Lung Neoplasms, Untreated Childhood Medulloblastoma, and Untreated Childhood Supratentorial Primitive Neuroectodermal Tumor. … Mitometh is under investigation for the treatment of Adenocarcinoma, Oropharyngeal Neoplasms, Nasopharyngeal Carcinoma, Non-small Cell Lung Cancer, and Stage IV Non-small Cell Lung Cancer, among others

  6. Drug

    Tasurgratinib

    go.drugbank.com/drugs/DB21222
    Investigational

    Tasurgratinib has a monoisotopic molecular weight of 587.27 Da. … The usage of the INN stem '-gratinib' in the name indicates that Tasurgratinib is a fibroblast growth factor receptor (FGFR) inhibitor.

  7. Drug

    EP-1043

    go.drugbank.com/drugs/DB06118
    Experimental

    The vaccine consists of a string of 18 HIV-derived major histocompatibility complex (MHC) Class II restricted epitopes, each separated by a spacer designed to optimize potency. … The epitopes included in the vaccine were selected using Epitope Identification System (EIS) and each of them is predicted to be recognized in the majority of the prospective patient population.

  8. Drug

    Diazepinomicin

    go.drugbank.com/drugs/DB12420
    Investigational

    Diazepinomicin has been used in trials studying the treatment of Glioblastoma Multiforme.

  9. Drug

    Florfenicol

    go.drugbank.com/drugs/DB11413
    ExperimentalVet approved

    Florfenicol is a fluorinated synthetic analog of thiamphenicol.

  10. Drug

    IDM-1

    go.drugbank.com/drugs/DB05292
    Experimental

    IDM-1 is IDM’s most advanced antibody-based Cell drug for the treatment of cancer. … It is comprised of MAK(Monocytes-derived Activated Killer) cells associated with MDX-210, a bispecific anti-HER-2/neu antibody developed by Medarex Inc.