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Iclepertin
go.drugbank.com/drugs/DB19058InvestigationalIclepertin is under investigation in clinical trial NCT05211947 (A Study to Test Long-term Safety of Iclepertin in People With Schizophrenia Who Took Part in a Previous CONNEX Study).
Esaxerenone
go.drugbank.com/drugs/DB15207InvestigationalEsaxerenone is under investigation in clinical trial NCT02722265 (Long-term Study of CS-3150 as Monotherapy or in Combination With Other Antihypertensive Drug in Japanese Patients With Essential Hypertension
Balcinrenone
go.drugbank.com/drugs/DB15418InvestigationalAZD-9977 is under investigation in clinical trial NCT03843060 (A Phase 1 Study to Assess the Pharmacokinetics of AZD9977 Administered Alone and in Combination With Itraconazole in Healthy Volunteers).
HEC-921
go.drugbank.com/drugs/DB33971ExperimentalHEC-921 is under investigation in clinical trial NCT07824934 (HEC-921 Injection as Monotherapy and in Combination With Antineoplastic Therapies in Patients With Advanced Malignant Solid Tumors). … HEC-921 is a biologic drug.
Pimicotinib
go.drugbank.com/drugs/DB18972InvestigationalIt was initially developed by Abbisko Therapeutics Co in collaboration with Merck KGaA. [L53748] Pimicotinib was granted Fast Track Designation in December 2023 by the FDA. [L53753] … Pimicotinib is under investigation in clinical trial NCT05804045 (Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER)).
Synonyms: 1-Pyrrolidinecarboxamide, 3,3-dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-, 3,3-Dimethyl-N-[6-methyl-5-[[2-(1-methyl-1H-pyrazol-4-yl)-4-pyridinyl]oxy]-2-pyridinyl]-2-oxo-1-pyrrolidinecarboxamideImnopitant
go.drugbank.com/drugs/DB21456ExperimentalImnopitant is a small molecule drug. The usage of the INN stem '-pitant' in the name indicates that Imnopitant is a neurokinin NK1 (substance P) receptor antagonist.
Libvatrep
go.drugbank.com/drugs/DB21488ExperimentalLibvatrep is a small molecule drug. The usage of the INN stem '-vatrep' in the name indicates that Libvatrep is a transient receptor potential vanilloid (TRPV) antagonist.
Pramiverine
go.drugbank.com/drugs/DB19588ExperimentalPramiverine is a small molecule drug. The usage of the INN stem '-verine' in the name indicates that Pramiverine is a spasmolytic with a papaverine-like action.
Mofegiline
go.drugbank.com/drugs/DB19621ExperimentalMofegiline is a small molecule drug. The usage of the INN stem '-giline' in the name indicates that Mofegiline is a monoamine oxydase (MAO)-inhibitor type B.
Elpetrigine
go.drugbank.com/drugs/DB19653ExperimentalElpetrigine is a small molecule drug. The usage of the INN stem '-trigine' in the name indicates that Elpetrigine is a sodium channel blocker, signal transduction modulator.