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Displaying results 8071 - 8080 of 8695 in total
  1. Drug

    Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

    go.drugbank.com/drugs/DB16443
    Investigational

    It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. … The Recombinant SARS-CoV-2 Vaccine was created by inserting genes of the SARS-CoV-2 spike protein’s receptor-binding domain into a baculovirus expression system[F4738, A226853].

  2. Drug

    Tunicamycin

    go.drugbank.com/drugs/DB13172
    Experimental

    Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. … It is used as an experimental tool to induce unfolded protein response. Tunicamycin is produced by Streptomyces clavuligerus and Streptomyces lysosuperficus bacteria along with several other species.

  3. Drug

    SC-236

    go.drugbank.com/drugs/DB14059
    Experimental

    SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , .

  4. Drug

    Cinitapride

    go.drugbank.com/drugs/DB08810
    Investigational

    Cinitapride is a gastroprokinetic agent and antiulcer benzamide with agonist activity at 5-HT1 and 5-HT4 receptors and antagonist activity at 5-HT2 receptors. It is marketed in Spain and Mexico.

    Categories: Drugs for Functional Gastrointestinal Disorders, Serotonin Receptor Agonists
  5. Drug

    AV-COVID-19

    go.drugbank.com/drugs/DB15802
    Investigational

    As of July 2020, the company is pursuing an adaptive Phase IB-II Randomized Clinical Trial (NCT04386252) to test the vaccine.

  6. Drug

    Namodenoson

    go.drugbank.com/drugs/DB12885
    Investigational

    Namodenoson has been used in trials studying the treatment of Chronic Hepatitis C and Hepatocellular Carcinoma.

    Categories: Purinergic P1 Receptor Agonists
  7. Drug

    MVA-BN-brachyury-TRICOM vaccine

    go.drugbank.com/drugs/DB17424
    Investigational

    MVA-BN-brachyury-TRICOM vaccine is an investigational cancer vaccine.

  8. Drug

    DPCPX

    go.drugbank.com/drugs/DB12946
    Investigational

    CPX has been used in trials studying the treatment of Cystic Fibrosis.

    Categories: Purinergic P1 Receptor Antagonists, Adenosine A1 Receptor Antagonists
  9. Drug

    Quingestanol

    go.drugbank.com/drugs/DB13685
    Experimental

    Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 Substrates
  10. Drug

    Stanolone

    go.drugbank.com/drugs/DB02901
    IllicitInvestigational

    A potent androgenic metabolite of testosterone. Dihydrotestosterone (DHT) is generated by a 5-alpha reduction of testosterone. Unlike testosterone, DHT cannot be aromatized to estradiol therefore DHT is considered a pure androgenic steroid.

    Categories: P-glycoprotein substrates, Anabolic Agents for Systemic Use