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Fursultiamine
go.drugbank.com/drugs/DB08966ApprovedIt has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
Reloxiliase
go.drugbank.com/drugs/DB17653ExperimentalReloxiliase is a first-in-class, oral crystalline formulation of the oxalate-specific, microbial enzyme oxalate decarboxylase. It is being investigated for the treatment of hyperoxaluria.[A258823]
WP-1301
go.drugbank.com/drugs/DB17702ExperimentalWP1301 is a synthetic peptide derived from hFVIII. It binds to an MHC class II molecule and is recognized by a Factor VIII-specific T cell.[L46138]
BMS-830216
go.drugbank.com/drugs/DB14787InvestigationalBMS-830216 is under investigation in clinical trial NCT00909766 (Safety, Pharmacokinetics and Pharmacodynamics Study to Evaluate BMS-830216 in Obese Subjects).
Cobitolimod
go.drugbank.com/drugs/DB14819InvestigationalCobitolimod is under investigation in clinical trial NCT03178669 (The Efficacy of Cobitolimod in Patients With Moderate to Severe Active Ulcerative Colitis).
Bimiralisib
go.drugbank.com/drugs/DB14846InvestigationalBimiralisib is under investigation in clinical trial NCT02723877 (PQR309 and Eribulin in Metastatic HER2 Negative and Triple-negative Breast Cancer (PIQHASSO)).
Lucerastat
go.drugbank.com/drugs/DB14872InvestigationalLucerastat is under investigation in clinical trial NCT03425539 (Efficacy and Safety of Lucerastat Oral Monotherapy in Adult Subjects With Fabry Disease).
Derazantinib
go.drugbank.com/drugs/DB14889InvestigationalDerazantinib is under investigation in clinical trial NCT03230318 (Derazantinib in Subjects With FGFR2 Gene Fusion Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma).
Camidanlumab tesirine
go.drugbank.com/drugs/DB16411InvestigationalCamidanlumab tesirine is under investigation in clinical trial NCT04639024 (ADCT-301 in Patients With R/R AML, MDS, or MDS/MPN).
HRS-1167
go.drugbank.com/drugs/DB18703InvestigationalHRS-1167 is under investigation in clinical trial NCT05473624 (Study of HRS-1167 as Monotherapy in Patients With Advanced Solid Tumors).