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Displaying results 8151 - 8160 of 10000 in total
  1. Drug

    Parimifasor

    go.drugbank.com/drugs/DB21146
    Experimental

    Parimifasor is a small molecule drug. Parimifasor has a monoisotopic molecular weight of 459.03 Da.

  2. Drug

    Dosergoside

    go.drugbank.com/drugs/DB21177
    Experimental

    Dosergoside is a small molecule drug. Dosergoside has a monoisotopic molecular weight of 551.41 Da.

  3. Drug

    Posaraprost

    go.drugbank.com/drugs/DB21227
    Experimental

    Posaraprost is a small molecule drug. Posaraprost has a monoisotopic molecular weight of 410.25 Da.

  4. Drug

    Peforelin

    go.drugbank.com/drugs/DB21255
    Experimental

    Peforelin is a small molecule drug. The usage of the INN stem '-relin' in the name indicates that Peforelin is a pituitary hormone-release stimulating peptide. … Peforelin has a monoisotopic molecular weight of 1258.56 Da.

  5. Drug

    rAAV9-CMV-hNAGLUop

    go.drugbank.com/drugs/DB33959
    Experimental

    rAAV9-CMV-hNAGLUop is a biologic drug. rAAV9-CMV-hNAGLUop is under investigation in clinical trial NCT07818759 (Single Injection of rAAV9-CMV-hNAGLUop Gene for Patients With Mucopolysaccharidosis (MPS)

  6. Drug

    Asparaginase Erwinia chrysanthemi

    go.drugbank.com/drugs/DB08886
    ApprovedInvestigational

    Asparaginase _Erwinia chrysanthemi_ is an asparaginase-specific enzyme derived from _Erwinia_ _chrysanthemi_ used as an anticancer agent. … [L1448] L-asparaginase was first identified in 1963,[A236344] and there are different formulations of L-asparaginase, including [Asparaginase Escherichia coli] and a pegylated form of this enzyme, [Pegaspargase

    Synonyms: Erwinia L-asparaginase, L-asparaginase (Erwinia)
  7. Drug

    Carfilzomib

    go.drugbank.com/drugs/DB08889
    ApprovedInvestigational

    Carfilzomib is an injectable antineoplastic agent (IV only). Chemically, it is a modified tetrapeptidyl epoxide and an analog of epoxomicin. It is also a selective proteasome inhibitor. … FDA approved carfilzomib in July 2012 for the treatment of adults with relapsed or refractory multiple myeloma as monotherapy or combination therapy.[L39392]

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsProducts: KYPROLIS®, KARFIB®
  8. Drug

    Teduglutide

    go.drugbank.com/drugs/DB08900
    ApprovedInvestigational

    Teduglutide is a glucagon-like peptide-2 (GLP-2) analogue. It is made up of 33 amino acids and is manufactured using a strain of Escherichia coli modified by recombinant DNA technology. … The significance of this substitution is that teduglutide is longer acting than endogenous GLP-2 as it is more resistant to proteolysis from dipeptidyl peptidase-4. FDA approved on December 21, 2012.

    Categories: Glucagon-like Peptide-2 (GLP-2) Agonists, GLP-2 AnalogSynonyms: Gly(2)-GLP-2, (Gly2)GLP-2
  9. Drug

    Dimethyl fumarate

    go.drugbank.com/drugs/DB08908
    ApprovedInvestigational

    It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated … Dimethyl fumarate is an agent indicated for the treatment of relapsing forms of multiple sclerosis.

    Synonyms: (E)-But-2-enedioic acid dimethyl esterProducts: DIFUMY-MS®240 MG CÁPSULAS DURA, YARDIX® 240MG
  10. Drug

    Ferric carboxymaltose

    go.drugbank.com/drugs/DB08917
    ApprovedInvestigational

    Ferric carboxymaltose is an iron replacement product and, chemically, an iron-carbohydrate complex. It was FDA approved on July 25, 2013.

    Categories: Compounds used in a research, industrial, or household settingProducts: FERINJECT®, Ferinject® 50 mg iron/mL solution for injection/infusion