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TPX-4589
go.drugbank.com/drugs/DB18604InvestigationalTPX-4589 is an antibody-drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAE.
Synonyms: Antibody drug conjugate composed of a humanized monoclonal antibody targeting CLDN18.2 and linker-payload MC-VC-PAB-MMAEVCA-894A
go.drugbank.com/drugs/DB18609InvestigationalVCA-894A is a synthetic 2'-O-methoxyethyl phosphorothioate oligoribonucleotide sodium salt consisting of 19 nucleotide residues with the sequence 5'-MeCMeUGMeUGGAAGMeUGAGGGMeCMeCAG-3'
PRG-A01
go.drugbank.com/drugs/DB18613InvestigationalPRG-A01 is a novel inhibitor of Cu, Zn-superoxide dismutase (SOD1) misfolding and aggregation.
Givastomig
go.drugbank.com/drugs/DB18618InvestigationalGivastomig is an anti-Claudin 18.2 and 4.1BB bispecific antibody.
ABBV-011
go.drugbank.com/drugs/DB18622InvestigationalABBV-011 is an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicin.
Synonyms: an antibody-drug conjugate of humanized, cysteine-engineered IgG1 monoclonal antibody targeting seizure-related 6 homolog conjugated to N-acetyl-gamma-calicheamicinCTX130
go.drugbank.com/drugs/DB18627InvestigationalCTX130 is an allogeneic CRISPR/Cas9-mediated genetically modified CAR T cell therapy targeting CD70 antigen.
Synonyms: Allogeneic CRISPR/Cas9-mediated genetically modified CAR T cells targeting CD70 antigenNerispirdine
go.drugbank.com/drugs/DB12714InvestigationalNerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingMSX-122
go.drugbank.com/drugs/DB12715InvestigationalMSX-122 has been used in trials studying the treatment of Solid Tumors.
Categories: Heterocyclic Compounds, 1-RingTurofexorate isopropyl
go.drugbank.com/drugs/DB12719InvestigationalFxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl in Healthy Japanese Men).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRO-5028442
go.drugbank.com/drugs/DB12721InvestigationalRO5028442 has been used in trials studying Autistic Disorder.
Categories: Heterocyclic Compounds, 2-Ring