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Tozorakimab
go.drugbank.com/drugs/DB16473Investigationalhistory of exacerbations), and NCT06040086 (recruiting; symptomatic COPD with a history of exacerbations). … Tozorakimab (MEDI3506), developed by AstraZeneca, was investigated in multiple clinical trials to evaluate its safety, tolerability, efficacy, and pharmacokinetics across various conditions.
Synonyms: ) L123>M (121)) CDR-IMGT [8.8.19] (26-33.51-58.97-1, Immunoglobulin G1, anti-(human interleukin 33) (human monoclonal MEDI3506 γ1-chain), disulfide with human monoclonal MEDI3506 λ-chain, dimerG4544
go.drugbank.com/drugs/DB05244ExperimentalG4544 is an oral gallium compound that enables oral absorption of the active ingredient contained in Ganite™ (gallium nitrate injection). … It targets bone tissue and is actively incorporated into bone mineral at sites where bone is metabolically active.
AK119
go.drugbank.com/drugs/DB16423InvestigationalAK119 is a humanized anti-CD73 monoclonal antibody being investigated in the clinical trial NCT04516564 (A Study of AK119 (Anti-CD73 Antibody), a Treatment for COVID-19, in Healthy Subjects).[L28315]
Neramexane
go.drugbank.com/drugs/DB04926InvestigationalNeramexane is a low-to-moderate affinity uncompetitive NMDA receptor antagonist.
PF-4191834
go.drugbank.com/drugs/DB11645InvestigationalPF-4191834 has been investigated for the basic science of Asthma.
Categories: Heterocyclic Compounds, 1-RingFedovapagon
go.drugbank.com/drugs/DB11734InvestigationalFedovapagon has been used in trials studying the treatment of Nocturia.
Brivanib alaninate
go.drugbank.com/drugs/DB11865InvestigationalBrivanib alaninate has been investigated for the treatment of Colorectal Cancer.
Categories: Heterocyclic Compounds, 1-RingDalcetrapib
go.drugbank.com/drugs/DB12181InvestigationalDalcetrapib is under investigation for the treatment of Acute Coronary Syndrome.
VP-14637
go.drugbank.com/drugs/DB12195InvestigationalMDT-637 has been investigated for the treatment of Drug Safety.
Categories: Heterocyclic Compounds, 1-RingTozadenant
go.drugbank.com/drugs/DB12203InvestigationalTozadenant has been investigated for the basic science of Cocaine Dependence.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring