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Zilebesiran
go.drugbank.com/drugs/DB18929InvestigationalZilebesiran is under investigation in clinical trial NCT06272487 (Zilebesiran as Add-on Therapy in Patients With High Cardiovascular Risk and Hypertension Not Adequately Controlled by Standard of Care … Antihypertensive Medications (KARDIA-3)).
Synonyms: (2S,4R)-1-{1-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]-16,16-bis({3-[(3-{5-[(2- acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanamido}propyl)amino]-3-oxopropoxy}methyl)-5,11,18-trioxo-14-oxa-6,10,17, - triazanonacosan-29-oyl}-4-hydroxypyrrolidin-Abivertinib
go.drugbank.com/drugs/DB15327InvestigationalThe study is expected to be completed in March 2021.[L17398] … [L17383] It has been investigated for use in the treatment of non-small cell lung cancer (NSCLC) and B-cell malignancies.
Categories: Heterocyclic Compounds, 1-RingZonampanel anhydrous
go.drugbank.com/drugs/DB20448InvestigationalZonampanel anhydrous is under investigation in clinical trial NCT00044070 (A Study to Evaluate the Effects of YM872 on Stroke Lesion Volume in Acute Stroke Patients). … Zonampanel anhydrous is a small molecule drug.
Cinuperone
go.drugbank.com/drugs/DB19498ExperimentalCinuperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Cinuperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative. … Cinuperone has a monoisotopic molecular weight of 377.19 Da.
Declenperone
go.drugbank.com/drugs/DB19700ExperimentalDeclenperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Declenperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative. … Declenperone has a monoisotopic molecular weight of 381.19 Da.
Dasantafil
go.drugbank.com/drugs/DB19918ExperimentalDasantafil is a small molecule drug. The usage of the INN stem '-afil' in the name indicates that Dasantafil is a inhibitor of phosphodiesterase PDE5 with vasodilator action. … Dasantafil has a monoisotopic molecular weight of 521.13 Da.
Tauromustine
go.drugbank.com/drugs/DB19978ExperimentalTauromustine is a small molecule drug. The usage of the INN stem '-mustine' in the name indicates that Tauromustine is a antineoplastic, alkylating agent, (β-chloroethyl) amine derivative. … Tauromustine has a monoisotopic molecular weight of 286.05 Da.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesRecainam
go.drugbank.com/drugs/DB20085ExperimentalRecainam is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Recainam is a class I antiarrhythmic, procainamide and lidocaine derivative. … Recainam has a monoisotopic molecular weight of 263.2 Da.
Bucainide
go.drugbank.com/drugs/DB20650ExperimentalBucainide is a small molecule drug. The usage of the INN stem '-cain-' in the name indicates that Bucainide is a class I antiarrhythmic, procainamide and lidocaine derivative. … Bucainide has a monoisotopic molecular weight of 329.28 Da.
Categories: Heterocyclic Compounds, 1-RingPrideperone
go.drugbank.com/drugs/DB20207ExperimentalPrideperone is a small molecule drug. The usage of the INN stem '-perone' in the name indicates that Prideperone is a tranquillizer, neuroleptic, 4'-fluoro-4-piperidinobutyrophenone derivative. … Prideperone has a monoisotopic molecular weight of 409.18 Da.