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Tanespimycin
go.drugbank.com/drugs/DB05134InvestigationalTanespimycin, manufactured by Conforma Therapeutics is under development as a small molecule inhibitor of heat shock protein 90 (HSP90).
ABBV-514
go.drugbank.com/drugs/DB17586InvestigationalABBV-514 is in development for the treatment of non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor.[L45464]
D-threo-neopterin
go.drugbank.com/drugs/DB02385Experimental(From Stedman, 26th ed) Neopterin also serves as a precursor in the biosynthesis of biopterin.
GX-19 Vaccine
go.drugbank.com/drugs/DB15891InvestigationalAs of June 2020, the vaccine candidate is undergoing Phase I and Phase IIa trials to determine dose levels for safety and efficacy[A219758,L16488].
Bambermycins
go.drugbank.com/drugs/DB11377ExperimentalVet approvedThey are used as an additive in food ingested by chickens and swine. The bambermycin complex of antibiotics consists primarily of moenomycins A and C.
Epratuzumab
go.drugbank.com/drugs/DB04958InvestigationalThis agent may subsequently be well matched for use in oncology and the treatment of inflammatory autoimmune disorders, such as lupus.
Cimicoxib
go.drugbank.com/drugs/DB05095InvestigationalCimicoxib is a selective COX-2 inhibitor being developed by Affectis as a treatment for depression and schizophrenia.
Lixmabegagene relduparvovec
go.drugbank.com/drugs/DB16816InvestigationalLixmabegagene relduparvovec, formerly known as LYS-GM101, is a recombinant adeno-associated virus vector serotype rh.10 (AAVrh.10) carrying the human β-galactosidase gene (GBL1).
Nurulimab
go.drugbank.com/drugs/DB18946InvestigationalNurulimab is under investigation in clinical trial NCT05732805 (A Clinical Study of BCD-217 (Nurulimab + Prolgolimab) Followed by Anti-pd-1 Compared to Anti-pd-1 Monotherapy as First-line Treatment in
Tricaine
go.drugbank.com/drugs/DB11552ExperimentalVet approvedTricaine (as tricaine methanesulfonate) is white powder used for anesthesia, sedation, or euthanasia of fish.