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Displaying results 8281 - 8290 of 10000 in total
  1. Drug

    GLB-004

    go.drugbank.com/drugs/DB32796
    Experimental

    GLB-004 is a molecular glue degrader targeting ARNT(HIF-1β).[L56125, L56126]

  2. Drug

    GLB-005

    go.drugbank.com/drugs/DB32797
    Experimental

    GLB-005 is a molecular glue degrader targeting WIZ and is being investigated for treatment of sickle cell disease and β-thalassemia.[L56125, L56126, L56128]

  3. Drug

    GLB-007

    go.drugbank.com/drugs/DB32798
    Experimental

    GLB-007 is a molecular glue degrader targeting WIZ and ZBTB7A.[L56125, L56126, L56128]

  4. Drug

    GLB-006

    go.drugbank.com/drugs/DB32799
    Experimental

    GLB-006 is a molecular glue degrader targeting NEK7.[L56125, L56126]

  5. Drug

    RS5441

    go.drugbank.com/drugs/DB33178
    Experimental

    RS5441, also known as ET-02, is a small molecule topical medication investigated for male pattern baldness and age-related alopecia.[L57508, L57509]

  6. Drug

    Reteplase

    go.drugbank.com/drugs/DB00015
    ApprovedInvestigationalWithdrawn

    Retavase is a deletion mutein of human tPA formed by deleting various amino acids present in endogenous human tPA. … Retavase is considered a "third-generation" thrombolytic agent, genetically engineered to retain and delete certain portions of human tPA.

    Synonyms: Human t-PA (residues 1-3 and 176-527)
  7. Drug

    Sargramostim

    go.drugbank.com/drugs/DB00020
    ApprovedInvestigational

    Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. … Substitution of Leu23 leads to a difference from native protein.

  8. Drug

    Palifermin

    go.drugbank.com/drugs/DB00039
    ApprovedInvestigational

    Palifermin is a recombinant human keratinocyte growth factor (KGF). It is 140 residues long, and is produced using E. coli. Palifermin was granted FDA approval on 15 December 2004.[L17933]

  9. Drug

    Glucagon

    go.drugbank.com/drugs/DB00040
    ApprovedInvestigational

    Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.

    Synonyms: Glucagon (recombinant dna origin)
  10. Drug

    Pegvisomant

    go.drugbank.com/drugs/DB00082
    ApprovedInvestigational

    Pegvisomant is a highly selective growth hormone (GH) receptor antagonist. It is used to treat acromegaly.