Search
Zileuton
go.drugbank.com/drugs/DB00744ApprovedWithdrawnThe immediate release tablet of Zileuton has been withdrawn from the US market.
Medium-chain triglycerides
go.drugbank.com/drugs/DB13959ApprovedInvestigationalMedium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms.
Pork collagen
go.drugbank.com/drugs/DB14100ApprovedThe surgical implantation shows a tolerable safety profile and efficacy up to 4 years, but it is not indicated for patients with osteoarthritis.
Telisotuzumab vedotin
go.drugbank.com/drugs/DB15104ApprovedInvestigational[L53193] Telizotuzumab vedotin-tllv was approved by the US FDA in May 2025 for previously treated advanced NSCLC patients with high c-Met protein overexpression,[L53158,L53183] becoming the first treatment
Resorcinol
go.drugbank.com/drugs/DB11085ApprovedInvestigationalResorcinol is a 1,3-isomer (or meta-isomer) of benzenediol with the formula C6H4(OH)2. It is used as an antiseptic and disinfectant in topical pharmaceutical products in the treatment of skin disorders and infections such as acne, seborr...
Mixtures: Up and up vagicaineDefactinib
go.drugbank.com/drugs/DB12282ApprovedInvestigational[L53208,A273943] Defactinib was approved by the US FDA in May 2025 in a co-package alongside [avutometinib] (called Avmapki Fakzynja) for the treatment of recurrent KRAS-mutated low-grade serous ovarian
Viloxazine
go.drugbank.com/drugs/DB09185ApprovedInvestigationalWithdrawnIn the US, viloxazine was assigned an orphan drug designation in 1984 under the brand name CATATROL: while this product was intended to treat cataplexy and narcolepsy, the drug was never approved for these
Ivermectin
go.drugbank.com/drugs/DB00602ApprovedInvestigationalVet approvedIvermectin is a semi-synthetic antiparasitic medication derived from avermectins, a class of highly-active broad-spectrum antiparasitic agents isolated from the fermentation products of Streptomyces avermitilis. Ivermectin itself is a mi...
Mixtures: Heartgard Plus Chewable Tablet for Dogs - Up to 25 lbsAfamelanotide
go.drugbank.com/drugs/DB04931Approved[L9092] Despite its relatively recent approval, afamelanotide has been available for use as an orphan drug in both the US and EU since 2008.[L9122,L9125]
Peramivir
go.drugbank.com/drugs/DB06614ApprovedInvestigationalThe development of peramivir has been supported by the US Department of Health and Human Services as part of the government's effort to prepare for a flu pandemic.