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Displaying results 8441 - 8450 of 10000 in total
  1. Drug

    JZP-386 free base

    go.drugbank.com/drugs/DB17068
    Experimental

    JZP-386 is a deuterium-containing analog of sodium oxybate. Its safety, pharmacokinetics and pharmacodynamics were evaluated in clinical trial NCT02215499.

  2. Drug

    MYR-101

    go.drugbank.com/drugs/DB17075
    Investigational

    It is caused by a mutation in the aspartoacylase gene (_ASPA_), which leads to a deficiency of the aspartoacylase enzyme (ASPA). … Canavan disease is a fatal childhood genetic disorder characterized by white matter degeneration in the brain.

  3. Drug

    Sipagladenant

    go.drugbank.com/drugs/DB17080
    Investigational

    KW-6356 is a selective antagonist of adenosine A2A receptors developed by Kyowa Kirin.[L43822]

  4. Drug

    Tinlorafenib

    go.drugbank.com/drugs/DB17082
    Investigational

    Tinlorafenib (PF-07284890) is a potent, selective, highly brain-penetrant, small-molecule inhibitor of BRAF V600 mutations.[A253992]

  5. Drug

    KDT-3594

    go.drugbank.com/drugs/DB17085
    Investigational

    KDT-3594 is a non-ergot dopamine receptor agonist developed by Kissei Pharmaceutical.

  6. Drug

    OTX-2002

    go.drugbank.com/drugs/DB17246
    Investigational

    OTX-2002 is a bicistronic messenger ribonucleic acid (mRNA) encoding for ZF-DNMT and ZF-KRAB proteins, encapsulated in a lipid nanoparticle (LNP).

  7. Drug

    ST101 peptide

    go.drugbank.com/drugs/DB17272
    Experimental

    ST101 is a cell-penetrating peptide that disrupts the protein-protein interactions driving ATF5-regulated gene transcription.

  8. Drug

    Lutetium Lu177 Edotreotide

    go.drugbank.com/drugs/DB17278
    Investigational

    Synonyms: Dotatoc Lu-177, Edotreotide lutetium Lu-177Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    IMAB027

    go.drugbank.com/drugs/DB17282
    Investigational

    IMAB027 is a chimeric monoclonal antibody against Claudin 6.

  10. Drug

    Tavokinogene telseplasmid

    go.drugbank.com/drugs/DB17301
    Investigational

    Tavokinogene telseplasmid consists of a DNA Plasmid Vector Encoding IL-12.

    Synonyms: Dna plasmid containing genes coding for the human interleukin 12 (il-12) p35 and p40 subunits that are separated by an internal ribosomal entry site (ires) and under the control of a single cytomegalovirus