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Linerixibat
go.drugbank.com/drugs/DB11729ApprovedInvestigational[A275481, A275482] On March 19, 2026, linerixibat was approved by the FDA for the treatment of cholestatic pruritus in patients with primary biliary cholangitis (PBC). … Linerixibat is a first-in-class and small-molecule inhibitor of the ileal bile acid transporter (IBAT).
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP3A InhibitorsSynonyms: 3-((((3R,5R)-3-BUTYL-3-ETHYL-7-METHOXY-1,1-DIOXO-5-PHENYL-2,3,4,5-TETRAHYDRO- 1H-1.LAMBDA.6,4-BENZOTHIAZEPIN-8-YL)METHYL)AMINO)PENTANEDIOIC ACID, PENTANEDIOIC ACID, 3-((((3R,5R)-3-BUTYL-3-ETHYL-2,3,4,5-TETRAHYDRO-7-METHOXY-1,1-DIOXIDO-5-PHENYL-1,4-BENZOTHIAZEPIN-8-YL)METHYL)AMINO)-Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-Diphosphate
go.drugbank.com/drugs/DB02937ExperimentalAdenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. [PubChem]
Synonyms: Gamma-Arsono-Beta, Gamma-Methyleneadenosine-5'-DiphosphateN-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide
go.drugbank.com/drugs/DB03693ExperimentalCategories: Heterocyclic Compounds, 2-RingSynonyms: N-(2-Aminoethyl)-5-Chloroisoquinoline-8-Sulfonamide2'-deoxycytidine-2'-deoxyadenosine-3',5'-monophosphate
go.drugbank.com/drugs/DB02573ExperimentalSynonyms: 2'-deoxycytidine-2'-deoxyadenosine-3',5'-monophosphate1-(3-METHYLPHENYL)-1H-BENZIMIDAZOL-5-AMINE
go.drugbank.com/drugs/DB07972ExperimentalSynonyms: 1-(3-METHYLPHENYL)-1H-BENZIMIDAZOL-5-AMINE2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE
go.drugbank.com/drugs/DB08184ExperimentalSynonyms: 2-(2-METHYLPHENYL)-1H-INDOLE-5-CARBOXIMIDAMIDE2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE
go.drugbank.com/drugs/DB08185ExperimentalSynonyms: 2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5'-MONOPHOSPHATE2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE
go.drugbank.com/drugs/DB08359ExperimentalSynonyms: 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL
go.drugbank.com/drugs/DB08634ExperimentalSynonyms: 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL5-Hydroxy-N-Propargyl-1(R)-Aminoindan
go.drugbank.com/drugs/DB04307ExperimentalSynonyms: 5-Hydroxy-N-Propargyl-1(R)-Aminoindan