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Displaying results 841 - 850 of 10000 in total
  1. Drug

    Rosoxacin

    go.drugbank.com/drugs/DB00817
    Approved

    Rosoxacin is a quinolone derivative antibiotic for the treatment of bacterial infection of respiratory tract, urinary tract, GI, CNS and immuno compromised patients. … Rosoxacin is known to be effective against penicillin resistant strains and is a single dose orally administered drug, which avoids all complications of parenteral administration seen with penicillin,

    Synonyms: 1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acidCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 CYP1A2 Inhibitors
  2. Drug

    AB-001

    go.drugbank.com/drugs/DB18009
    Investigational

    Synonyms: (1E, 4E, 6E)-1-(3, 5-dimethoxyphenyl)- 7-(4-hydroxy-3, 5dimethoxyphenyl) hepta- 1, 4, 6-trien-3-oneCategories: Heterocyclic Compounds, 2-Ring
  3. Drug

    Vactosertib

    go.drugbank.com/drugs/DB15310
    Investigational

    Vactosertib is under investigation in clinical trial NCT03724851 (Vactosertib in Combination With Pembrolizumab in Metastatic Colorectal or Gastric Cancer).

    Synonyms: 2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]anilineCategories: Heterocyclic Compounds, 1-Ring
  4. Drug

    (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE

    go.drugbank.com/drugs/DB08515
    Experimental

    Synonyms: (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE
  5. Drug

    KUS-121 free acid

    go.drugbank.com/drugs/DB18510
    Investigational

    Synonyms: 1-Naphthalenesulfonic acid, 4-amino-3-[2-[6-(4-fluoro-2-methylphenyl)-3-pyridinyl]diazenyl]-, 4-Amino-3-[[6-(4-fluoro-2-methylphenyl)pyridin-3-yl]azo]naphthalene-1-sulfonic acidCategories: Heterocyclic Compounds, 1-Ring
  6. Drug

    Tovinontrine

    go.drugbank.com/drugs/DB16193
    Investigational

    Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease). … Tovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor.

    Synonyms: 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A)PYRAZIN-8(7H)-ONE, 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin-8-one
  7. Drug

    Sisomicin

    go.drugbank.com/drugs/DB12604
    Investigational

    Sisomicin has been used in trials studying the treatment of Pyoderma.

    Synonyms: (2S-CIS)-4-O-(3-AMINO-6-(AMINOMETHYL)-3,4-DIHYDRO-2H-PYRAN-2-YL)-2-DEOXY-6-O-(3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-.BETA.-L-ARABINOPYRANOSYL)-D-STREPTAMINE, 2-DEOXY-4-O-(3-DEOXY-4-C-METHYL-3-(METHYLAMINO)-.BETA.-L-ARABINOPYRANOSYL)-6-O-(2,6-DIAMINO-2,3,4,6-TETRADEOXY-.ALPHA.-D-GLYCERO-HEX-4-ENOPYRANOSYL)-L-STREPTAMINECategories: Drugs that are Mainly Renally Excreted with a Narrow Therapeutic Index
  8. Drug

    Tienilic acid

    go.drugbank.com/drugs/DB04831
    ApprovedWithdrawn

    It was withdrawn in 1982 after case reports in the United States suggested a link between ticrynafen and hepatitis. (Manier et al., 1982) … Tienilic acid, or ticrynafen, is a diuretic drug with uric acid-lowering action which was marketed for the treatment of hypertension.

    Synonyms: (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid, 4-(2-Theonyl)-2,3-dichlorphenoxyessigsäureCategories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP2C9 Inhibitors
  9. Drug

    8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine

    go.drugbank.com/drugs/DB04505
    Experimental

    Synonyms: 8-(2-Chloro-3,4,5-Trimethoxy-Benzyl)-9-Pent-4-Ylnyl-9h-Purin-6-Ylamine
  10. Drug

    2-butoxy-9-(2,6-difluorobenzyl)-N-(2-morpholin-4-ylethyl)-9H-purin-6-amine

    go.drugbank.com/drugs/DB07937
    Experimental

    Synonyms: 2-butoxy-9-(2,6-difluorobenzyl)-N-(2-morpholin-4-ylethyl)-9H-purin-6-amine