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Belotecan
go.drugbank.com/drugs/DB12459InvestigationalBelotecan has been investigated for the treatment of Epithelial Ovarian Cancer.
Roluperidone
go.drugbank.com/drugs/DB13080InvestigationalRoluperidone has been used in trials studying the treatment of Schizophrenia.
Inactivated SARS-Cov-2 Vaccine
go.drugbank.com/drugs/DB15862InvestigationalDeveloped by Sinopharm's Wuhan Institute of Biological Products co., this vaccine consists of the WIV04 strain of SARS-CoV-2. … [A220158] Results from these trials showed low rates of adverse reactions and demonstrated immunogenicity.
MVA-BN-brachyury-TRICOM vaccine
go.drugbank.com/drugs/DB17424Investigationalof T-cell co-stimulatory molecules (TRICOM), which is comprised of the three human immune-enhancing co-stimulatory molecules B7-1, ICAM-1 and LFA-3. … [L44513] MVA-BN-brachyury-TRICOM vaccine is administered as a priming vaccine, followed by the administration of the fowlpox virus(FPV)‐Brachyury booster vaccine.
QRX-411
go.drugbank.com/drugs/DB17868ExperimentalIt addresses the underlying cause of Usher syndrome due to the c.7595-2144A>G mutation in the _USH2A_ gene.[L46777] … QRX-411 is a first-in-class RNA-based oligonucleotide designed to restore wild-type USH2A mRNA, leading to the production of the functional USH2A protein.
Cabamiquine
go.drugbank.com/drugs/DB21477InvestigationalCabamiquine has a monoisotopic molecular weight of 462.24 Da. … Cabamiquine is under investigation in clinical trial NCT05974267 (Efficacy, Safety, and PK of M5717 in Combination With Pyronaridine as Chemoprevention in Adults and Adolescents With Asymptomatic Plasmodium
SAR445136
go.drugbank.com/drugs/DB17708Investigational[A259063] It was formerly investigated for the treatment of beta-thalassemia, and it is currently being investigated for the treatment of sickle cell disease.[L46148] … It consists of autologous CD34+ hematopoietic stem precursor cells (HSPC) modified ex vivo by zinc finger nucleases (ZFN) that target the BCL11A gene erythroid-specific enhancer (ESE) to increase endogenous
Flizasertib
go.drugbank.com/drugs/DB21613InvestigationalFlizasertib has a monoisotopic molecular weight of 271.11 Da. … The usage of the INN stem '-sertib' in the name indicates that Flizasertib is a serine/threonine kinase inhibitor.
Racivir
go.drugbank.com/drugs/DB12753InvestigationalRacivir is a 50:50 mixture of [emtricitabine] and its positive enantiomer. Racivir has been used in trials studying the prevention of HIV Infections.
Oxabolone cipionate
go.drugbank.com/drugs/DB13185ExperimentalOxabolone cipionate is the C17β cypionate ester and a prodrug of [DB01500]. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone).