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Displaying results 8501 - 8510 of 10000 in total
  1. Drug

    NTLA-2002

    go.drugbank.com/drugs/DB17597
    Investigational

    NTLA-2002 is a lipid nanoparticle encapsulating single guide RNA (G012267) targeting the human KLKB1 gene and messenger RNA (mRNA000042) encoding Cas9.

  2. Drug

    Emprumapimod

    go.drugbank.com/drugs/DB17603
    Investigational

    Emprumapimod is a potent, orally active and selective inhibitor of p38α mitogen-activated kinase inhibitor. It was investigated for dilated cardiomyopathy.

  3. Drug

    Intermedine

    go.drugbank.com/drugs/DB17612
    Investigational

    Synonyms: Ac-ser-tyr-ser-met-glu-his-phe-arg-trp-gly-lys-pro-val-nh2, Valinamide, acetyl-l-seryl-l-tyrosyl-l-seryl-l-methionyl-l-glutamyl-l-histidyl-l-phenylalanyl-l-arginyl-l-tryptophyl-glycyl-l-lysyl-l-prolyl-, l-Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    PXL-770 free acid anhydrous

    go.drugbank.com/drugs/DB17615
    Experimental

    Synonyms: 2-chloro-3-(1-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-6-oxo- 5-phenyl-6,7-dihydrothieno(2, 3-b)pyridin-4-olateCategories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Mubodina

    go.drugbank.com/drugs/DB17616
    Experimental

    It is a recombinant human minibody directed against complement component C5.

    Synonyms: Neutralizing scFv dimer to C5 fused at the C terminal end to the Fc domains of human IgG1
  6. Drug

    Sinbaglustat

    go.drugbank.com/drugs/DB17619
    Experimental

    Synonyms: (2s,3r,4r,5s)-2-(hydroxymethyl)-1-pentyl-3,4,5-piperidinetriol, (2S,3R,4R,5S)-2-(Hydroxymethyl)-1-Pentylpiperidine-3,4,5-TriolCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Cyclocreatine

    go.drugbank.com/drugs/DB17624
    Experimental

    Synonyms: 1-carboxymethyl-2-imino-imidazolidine, 2-imino-1-imidazolidineacetic acidCategories: Heterocyclic Compounds, 1-Ring
  8. Drug

    INZ-701

    go.drugbank.com/drugs/DB17629
    Investigational

    INZ-701 is an enzyme replacement therapy under development with the intention to be used for the treatment of calcification disorders of the circulatory system, bones, and kidneys.

    Synonyms: Recombinant human ectonucleotide pyrophosphatase/phosphodiesterase 1 fused to the Fc fragment of IGG1 (INZ-701)
  9. Drug

    AGT-182

    go.drugbank.com/drugs/DB17630
    Investigational

    AGT-182 is an investigational enzyme replacement therapy engineered by the fusion of the iduronate-2-sulfatase (IDS) enzyme and a human insulin receptor monoclonal antibody.

    Synonyms: Recombinant human insulin receptor monoclonal antibody-fused iduronate 2-sulfatase
  10. Drug

    Nedosiran

    go.drugbank.com/drugs/DB17635
    ApprovedInvestigational

    This approval is based on the favorable results from the pivotal phase 2 PHYOX<sup>TM</sup>2 and interim data from the ongoing phase 3 PHYOX<sup>TM</sup>3 clinical trials.[L48325] … hyperoxaluria type 1 (PH1) and relatively preserved kidney function.