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Hetrombopag
go.drugbank.com/drugs/DB16184InvestigationalHetrombopag is under investigation in clinical trial NCT03976882 (Hetrombopag for the Treatment of Chemotherapy-induced Thrombocytopenia in Subjects With Malignancy.).
Categories: Heterocyclic Compounds, 1-RingHQP1351
go.drugbank.com/drugs/DB16185InvestigationalHQP1351 is under investigation in clinical trial NCT03883100 (A Pivotal Study of HQP1351 in Patients of Chronic Myeloid Leukemia in Accelerated Phase With T315I Mutation).
Categories: Heterocyclic Compounds, 1-RingLocnartecan
go.drugbank.com/drugs/DB16186InvestigationalPEN-866 is under investigation in clinical trial NCT03221400 (PEN-866 in Patients With Advanced Solid Malignancies).
Synonyms: Hsp90-targeted sn-38 conjugate pen-866Nerispirdine
go.drugbank.com/drugs/DB12714InvestigationalNerispirdine has been used in trials studying the treatment of Neuritis, Optic Nerve, and Multiple Sclerosis.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingMSX-122
go.drugbank.com/drugs/DB12715InvestigationalMSX-122 has been used in trials studying the treatment of Solid Tumors.
Categories: Heterocyclic Compounds, 1-RingTurofexorate isopropyl
go.drugbank.com/drugs/DB12719InvestigationalFxr 450 is under investigation in clinical trial NCT00509756 (Study Evaluating Turofexorate isopropyl in Healthy Japanese Men).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingRO-5028442
go.drugbank.com/drugs/DB12721InvestigationalRO5028442 has been used in trials studying Autistic Disorder.
Categories: Heterocyclic Compounds, 2-RingAZD-7295
go.drugbank.com/drugs/DB12724InvestigationalAZD7295 has been investigated for the treatment of Hepatitis C.
Dipraglurant
go.drugbank.com/drugs/DB12733InvestigationalIt is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).
Categories: Heterocyclic Compounds, 1-RingAmuvatinib
go.drugbank.com/drugs/DB12742InvestigationalAmuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. … Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA repair in cancer cells.
Synonyms: 1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-d)pyrimidin-4-yl-, 4-[1]Benzofuro[3,2-D]Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-CarbothioamideCategories: Heterocyclic Compounds, 1-Ring