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Displaying results 8551 - 8560 of 10000 in total
  1. Drug

    Dipraglurant

    go.drugbank.com/drugs/DB12733
    Investigational

    It is a metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator (NAM).

    Categories: Heterocyclic Compounds, 1-Ring
  2. Drug

    Amuvatinib

    go.drugbank.com/drugs/DB12742
    Investigational

    Amuvatinib is an oral, selective multi-targeted tyrosine kinase inhibitor that suppresses c-MET, c-RET and the mutant forms of c-KIT, PDGFR and FLT3. … Amuvatinib also suppresses Rad51 protein, a critical component of double-stranded DNA repair in cancer cells.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-Piperazinecarbothioamide, N-(1,3-benzodioxol-5-ylmethyl)-4-benzofuro(3,2-d)pyrimidin-4-yl-, 4-[1]Benzofuro[3,2-D]Pyrimidin-4-Yl-N-(1,3-Benzodioxol-5-Ylmethyl)Piperazine-1-Carbothioamide
  3. Drug

    CGI-1842

    go.drugbank.com/drugs/DB12744
    Investigational

    JI-101 has been used in trials studying the treatment of Cancer, Colon Cancer, Neuroendocrine, Ovarian Cancer, and Advanced Solid Tumors.

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    GSK-690693

    go.drugbank.com/drugs/DB12745
    Investigational

    GSK690693 has been used in trials studying the treatment of Tumor, CANCER, and Lymphoma.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Butylphthalide

    go.drugbank.com/drugs/DB12749
    Investigational

    Butylphthalide has been used in trials studying the prevention of Restenosis.

    Synonyms: 3-n-butylphthalide, DL-3-n-butylphthalideCategories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household setting
  6. Drug

    Bucindolol

    go.drugbank.com/drugs/DB12752
    Investigational

    Bucindolol has been investigated in Heart Failure.

    Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor Antagonists
  7. Drug

    TAK-901

    go.drugbank.com/drugs/DB12756
    Investigational

    TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  8. Drug

    Opaganib

    go.drugbank.com/drugs/DB12764
    Investigational

    Opaganib, also known as ABC294640, is a selective [sphingosine kinase-2 (SK2)](https://go.drugbank.com/polypeptides/Q9NRA0) inhibitor that is orally administered.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-Pyridinylmethyl 3(4-Chlorophenyl)Adamantine Carboxamide, 4-Pyridinylmethyl-3-(4-Chlorophenyl) Adamantine Carboxamide
  9. Drug

    Veldoreotide

    go.drugbank.com/drugs/DB12777
    Investigational

    Somatoprim is under investigation for the treatment of Acromegaly.

  10. Drug

    Higenamine

    go.drugbank.com/drugs/DB12779
    Investigational

    Higenamine is under investigation in clinical trial NCT01451229 (Pharmacokinetics and Pharmacodynamics of Higenamine in Chinese Healthy Subjects).

    Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household setting