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FF-10501-01
go.drugbank.com/drugs/DB17554InvestigationalFF-10501-01 is a novel, selective inosine monophosphate dehydrogenase (IMPDH) inhibitor with anticancer activity. … [A257306] FF-10501-01 is under investigation in clinical trial NCT03486353 (A Study of FF-10501-01 in Combination With Azacitidine in Patients With Myelodysplastic Syndrome).
Nisevokitug
go.drugbank.com/drugs/DB17561InvestigationalNisevokitug is a monoclonal antibody targeted against transforming growth factor beta (TGFβ) under investigation in NCT04097821 (A Randomized, Open-label, Phase I/II Open Platform Study Evaluating Safety
QL1706
go.drugbank.com/drugs/DB17562InvestigationalQL1706 is an investigational bifunctional antibody that combines the activity of both PD-1 and CTLA-4 antibodies.
Belvarafenib
go.drugbank.com/drugs/DB17568InvestigationalSynonyms: 4-amino-n-(1-((3-chloro-2-fluorophenyl)amino)-6-methylisoquinolin-5-yl)thieno(3,2-d)pyrimidine-7-carboxamide, Thieno(3,2-d)pyrimidine-7-carboxamide, 4-amino-n-(1-((3-chloro-2-fluorophenyl)amino)-6-methyl-5-isoquinolinyl)-Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingDCVax-L
go.drugbank.com/drugs/DB17580InvestigationalDCVax-L is a personalized immunotherapy comprising an autologous vaccine with dendritic cells loaded _in vitro_ with autologous tumour lysate.
Synonyms: DCVax-LAd-CEA vaccine
go.drugbank.com/drugs/DB17581InvestigationalAd-CEA vaccine is a cancer immunotherapy composed of carcinoembryonic antigen (CEA).
Loxoribine
go.drugbank.com/drugs/DB17589ExperimentalSynonyms: 7-Allyl-7,8-dihydro-8-oxoguanosineCategories: Heterocyclic Compounds, 2-RingNP-6A4
go.drugbank.com/drugs/DB17599ExperimentalNP-6A4 is a peptide designed to specifically bind and activate angiotensin II receptor type 2 (AT2R). It has an Orphan Drug designation from the FDA for pediatric cardiomyopathy.[A258523]
Hemoximer
go.drugbank.com/drugs/DB17600InvestigationalHemoximer is a modified version of hemoglobin that undergoes pyridoxylation, for the purpose of lowering the oxygen affinity, and coupling with polyoxyethylene (POE), to increase its molecular weight.
Ixmyelocel-T
go.drugbank.com/drugs/DB17601InvestigationalIxmyelocel-T is an expanded, autologous multicellular therapy cultured from bone-marrow mononuclear cells. Developed by Vericel Corporation, it is being investigated for cardiomyopathy.
Synonyms: Ixmyelocel-T