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BRG01
go.drugbank.com/drugs/DB18173InvestigationalBRG01 is a genetically modified autologous CAR-T cell therapy under investigation for the treatment of nasopharyngeal carcinoma.[L48111]
CN-105
go.drugbank.com/drugs/DB18345InvestigationalCN-105 is a neuroprotective pentapeptide with the sequence Acetyl-Valine-Serine-Arginine-Arginine-Arginine-NH2 (Ac-VSRRR- NH2).
NFS-02
go.drugbank.com/drugs/DB18422InvestigationalNFS-02 is a recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene (rAAV2-ND1).
Synonyms: recombinant adeno-associated virus serotype 2 containing human mitochondrial ND1 codon optimized gene (rAAV2-ND1)Gefurulimab
go.drugbank.com/drugs/DB18928InvestigationalGefurulimab is under investigation in clinical trial NCT05556096 (Safety and Efficacy of ALXN1720 in Adults With Generalized Myasthenia Gravis).
Epaminurad
go.drugbank.com/drugs/DB18973InvestigationalEpaminurad is under investigation in clinical trial NCT05815901 (A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients).
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: (3,5-dibromo-4-hydroxyphenyl)(2,3-dihydro-4h-pyrido(4,3-b)-1,4-oxazin-4-yl)methanone, Methanone, (3,5-dibromo-4-hydroxyphenyl)(2,3-dihydro-4h-pyrido(4,3-b)-1,4-oxazin-4-yl)-Elebsiran
go.drugbank.com/drugs/DB19018InvestigationalElebsiran is under investigation in clinical trial NCT05461170 (SOLSTICE: Combination Therapy for the Treatment of Chronic Hepatitis D Infection.).
Orismilast
go.drugbank.com/drugs/DB19042InvestigationalOrismilast is under investigation in clinical trial NCT05190419 (Study to Assess the Efficacy and Safety of Orismilast in Psoriasis).
Synonyms: 2-(3,5-dichloro-1-oxido-4-pyridinyl)-1-(7-(difluoromethoxy)-2',3',5',6'-tetrahydro-1',1'-dioxidospiro(1,3-benzodioxole-2,4'-(4h)thiopyran)-4-yl)ethanoneLetolizumab
go.drugbank.com/drugs/DB19072InvestigationalLetolizumab is under investigation in clinical trial NCT02273960 (Study to Evaluate Safety and Efficacy in Adult Subjects With ITP).
Synonyms: Immunoglobulin (synthetic light chain variable region fragment) fusion protein with immunoglobulin g (synthetic fc fragment), noncovalently linked dimerVolenrelaxin
go.drugbank.com/drugs/DB21750InvestigationalVolenrelaxin is under investigation in clinical trial NCT06598631 (Efficacy and Safety of Volenrelaxin in Adults With Chronic Kidney Disease).
SB-705498
go.drugbank.com/drugs/DB11883InvestigationalSB-705498 has been investigated for the treatment of Rhinitis, Chronic Cough, and Non-allergic Rhinitis.
Categories: Heterocyclic Compounds, 1-Ring