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Mometasone
go.drugbank.com/drugs/DB00764ApprovedInvestigationalMometasone is a corticosteroid not currently used in medical products. [Mometasone furoate] however, is still in use.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: MOMECUTAN SALBE 1 MG/G, K-ALLEXIN %0,05 NAZAL SPREY 18 G 140 DOZVorinostat
go.drugbank.com/drugs/DB02546ApprovedInvestigationalVorinostat (rINN) or suberoylanilide hydroxamic acid (SAHA), is a drug currently under investigation for the treatment of cutaneous T cell lymphoma (CTCL), a type of skin cancer, to be used when the disease … It is the first in a new class of agents known as histone deacetylase inhibitors.
Products: ZOLINZA®VORINOSTAT 100 MG CAPSULASXylitol
go.drugbank.com/drugs/DB11195ApprovedInvestigationalThe recommended dose of xylitol for dental caries prevention is 6–10 g/day, and most adults can tolerate 40 g/day without adverse events [A22081]. … It is widely used as a sugar substitute and in "sugar-free" food products.
Mixtures: Fluor-a-day, Fluor-a-dayCategories: Compounds used in a research, industrial, or household settingBetahistine
go.drugbank.com/drugs/DB06698ApprovedInvestigationalIt has a significant impact on both the physical and social functioning of affected individuals. … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss.
Products: BETARIS 8 MG/ML ORAL DAMLA, 100 ML, BETARİS 24 MG TABLET, 100 ADETHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigational[A192132] **The FDA emergency use authorization for hydroxychloroquine and [chloroquine] in the treatment of COVID-19 was revoked on 15 June 2020. … [L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesProducts: HALOXIN TABLET 100 mg, PLAQUENIL 200 MG FILM KAPLI TABLET, 100 ADETIxabepilone
go.drugbank.com/drugs/DB04845ApprovedInvestigationalIxabepilone is a semisynthetic analogue of epothilone B. It has a lactone–lactam modification that minimizes susceptibility to esterase degradation. … Ixabepilone is an epothilone B analog developed by Bristol-Myers Squibb as a cancer drug.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexProducts: IXEMPRA FOR INJECTION 15 MG, IXEMPRA (FOR INJECTION 15 MG)Ipratropium
go.drugbank.com/drugs/DB00332ApprovedInvestigational[A176939] It is commonly administered through inhalation which allows producing a local effect without presenting a significant systemic absorption. … Ipratropium is a quaternary ammonium derivative of [atropine][A176957] that acts as an anticholinergic agent.
Mixtures: COMBIVENT OLCULU DOZ INHALATORLU AEROSOL 10 ML, İPRAVENT 20 MCG/100 MCG AEROSOL İNHALASYONU, SÜSPANSİYON (200 DOZ)Products: Aa-ipravent, A-TROFINSAChlorphenoxamine
go.drugbank.com/drugs/DB09007ApprovedWithdrawnChlorphenoxamine is marketed under the name Phenoxene. It is an antihistamine and anticholinergic used to treat itching as well as for its antiparkinsonian effect.
Products: SISTRAL 10 MG/ML I.V./I.M. ENJEKSİYONLUK ÇÖZELTİ, 6 ADET, SYSTRAL JEL, 20 GBleomycin
go.drugbank.com/drugs/DB00290ApprovedInvestigationalA complex of related glycopeptide antibiotics from <i>Streptomyces verticillus</i> consisting of bleomycin A2 and B2 (B2 CAS # 9060-10-0).
Products: BLEOCIN 15 MG LIYOFILIZE AMPUL, 1 ADET, BLEMISIN 15 MG LIYOFILIZE TOZ ICEREN FLAKON, 1 ADETVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalA full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … Specifically, varenicline is a partial agonist of the alpha4/beta2 subtype of the nicotinic acetylcholine receptor.
Mixtures: CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET, CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADETProducts: CHAMPIX 1.0 MG TABLETAS RECUBIERTAS, CHAMPIX 1 MG FILM KAPLI TABLET, 28 ADET