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STX-100
go.drugbank.com/drugs/DB16334InvestigationalSTX-100 is under investigation in clinical trial NCT01371305 (STX-100 in Patients With Idiopathic Pulmonary Fibrosis (IPF)).
Botensilimab
go.drugbank.com/drugs/DB16651InvestigationalBotensilimab is under investigation in clinical trial NCT03860272 (Fc-engineered Anti-ctla-4 Monoclonal Antibody in Advanced Cancer).
ASTX-029
go.drugbank.com/drugs/DB18900InvestigationalASTX-029 is under investigation in clinical trial NCT03520075 (Study of ASTX029 in Subjects With Advanced Solid Tumors).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingSynonyms: 2H-ISOINDOLE-2-ACETAMIDE, 6-(5-CHLORO-2-((TETRAHYDRO-2H-PYRAN-4-YL)AMINO)-4-PYRIMIDINYL)-N-((1S)-1-(3-FLUORO-5-METHOXYPHENYL)-2-HYDROXYETHYL)-1,3-DIHYDRO-.ALPHA.-METHYL-1-OXO-, (.ALPHA.R)-Tamnorzatinib
go.drugbank.com/drugs/DB19201InvestigationalTamnorzatinib is under investigation in clinical trial NCT03176277 (A Study of ONO-7475 in Patients With Acute Leukemias).
Synonyms: 3-quinolinecarboxamide, n-(5-((6,7-dimethoxy-4-quinolinyl)oxy)-2-pyridinyl)-1,2,5,6,7,8-hexahydro-2,5-dioxo-1-phenyl-, N-(5-((6,7-dimethoxyquinolin-4-yl)oxy)pyridin-2-yl)-2,5-dioxo-1-phenyl-1,2,5,6,7,8-hexahydroquinoline-3-carboxamideAbiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: (115-212), hinge 1-12 S10>P (222) (213-224), CH2 L, Gamma4 heavy chain humanized (1-441) [VH (Homo sapiens IGHV1-3*01 (83.7%) -(IGHD) -IGHJ4*01 (92.9%), CDR-IMGT [8.8.7] (26-33.51-58.97-103)) (1-114)-Homo sapiens IGHG4*01, nG4m(a) CH2 L92, G4v5 h P10 (CH1UB-612
go.drugbank.com/drugs/DB16444InvestigationalThis vaccine was designed to induce a broad immune response. It was able to reduce viral load and prevent COVID-19 infection in a mouse challenge model and in rhesus macaques[L30653, L30658]. … In rats, toxicity studies have so far shown favourable safety for this vaccine[L30653, L30658], Phase 1 trial is currently ongoing in Taiwan (NCT04545749).
Gestaclone
go.drugbank.com/drugs/DB21090ExperimentalGestaclone is a small molecule drug. The usage of the INN stem '-clone' in the name indicates that Gestaclone is a hypnotic tranquillizer. Gestaclone has a monoisotopic molecular weight of 370.17 Da.
Betoxycaine
go.drugbank.com/drugs/DB19475ExperimentalBetoxycaine is a small molecule drug. The usage of the INN stem '-caine' in the name indicates that Betoxycaine is a local anaesthetic. Betoxycaine has a monoisotopic molecular weight of 352.24 Da.
Motrazepam
go.drugbank.com/drugs/DB19799ExperimentalMotrazepam is a small molecule drug. The usage of the INN stem '-azepam' in the name indicates that Motrazepam is a diazepam derivative. Motrazepam has a monoisotopic molecular weight of 325.11 Da.
Oximonam
go.drugbank.com/drugs/DB19915ExperimentalOximonam is a small molecule drug. The usage of the INN stem '-monam' in the name indicates that Oximonam is a monobactam antibiotic. Oximonam has a monoisotopic molecular weight of 357.07 Da.
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring