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IBIO-100
go.drugbank.com/drugs/DB18233ExperimentalIBIO-100 is a high molecular weight multimer of E3-Fc, an endostatin C-terminus and IgG1-Fc fusion protein.
Sigvotatug Vedotin
go.drugbank.com/drugs/DB18377InvestigationalSigvotatug vedotin (SGN-B6A) is a humanized immunoglobulin G1 anti-integrin beta-6 monoclonal antibody conjugated to monomethyl auristatin E.
UV1
go.drugbank.com/drugs/DB18470ExperimentalUV1 is a cancer vaccine consisting of p719-20, p728, and p725 synthetic peptides representing fragments of the hTERT subunit
mRNA-3745
go.drugbank.com/drugs/DB18554InvestigationalmRNA-3745 is a lipid nanoparticle (LNP) encapsulated with nucleoside-modified, codon-optimized mRNAs encoding human glucose 6-phosphatase (G6Pase).
FCR001
go.drugbank.com/drugs/DB18595InvestigationalFCR001 is a somatic cell therapy product containing hematopoietic progenitor cells (HPC), Facilitating Cells (FC), and alpha beta T cells.
VOR33
go.drugbank.com/drugs/DB18624InvestigationalVOR33 is an allogeneic CRISPR/Cas9 genome-edited hematopoietic stem and progenitor cell (HSPC) therapy product lacking the CD33 protein.
Acapatamab
go.drugbank.com/drugs/DB18838InvestigationalAcapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Synonyms: (scfv)2-scfc, bispecific, Mmunoglobulin scfv-scfv-scfc, anti-(homo sapiens folh1 (folate hydrolase, prostate specific membrane antigen, psma)) and anti-(homo sapiens cd3e (cd3 epsilon, leu-4)), monoclonal antibody single chainZeluvalimab
go.drugbank.com/drugs/DB18868InvestigationalZeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Synonyms: Anti-pd-1 monoclonal antibody amg 404, Zeluvalimab (immunoglobulin g1-kappa, anti-(homo sapienspdcd1 (programmed cell death 1, pd-1, pd1, cd279)), monoclonal antibody)ANC-501
go.drugbank.com/drugs/DB18907InvestigationalANC-501 is under investigation in clinical trial NCT05439603 (ANC-501 in the Treatment of Adults With Major Depressive Disorder).
Categories: Heterocyclic Compounds, 1-RingSynonyms: 3-(3-Chlorophenyl)-1,5-dihydro-N-(1-methylethyl)-1-[4-[2-(4-morpholinyl)ethyl]phenyl]-5-oxo-4H-1,2,4-triazole-4-acetamideLorundrostat
go.drugbank.com/drugs/DB18957InvestigationalLorundrostat is under investigation in clinical trial NCT06153693 (Efficacy and Safety of Lorundrostat in Subjects With Uncontrolled and Resistant Hypertension).
Synonyms: 1-Piperazineacetamide, N-[trans-4-(acetylamino)cyclohexyl]-4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]-, N-(trans-4-acetamidocyclohexyl)-2-{4-[5-(4-methylphenyl)-1,2,4-triazin-3-yl]piperazin-1-yl}acetamide