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PS386113
go.drugbank.com/drugs/DB05211ExperimentalPS386113 is a small molecule drug candidate under investigation for the treatment of inflammatory disorders. It is being developed by Schering-Plough and Pharmacopeia.
BBM-H901
go.drugbank.com/drugs/DB17704InvestigationalBBM-H901 is a liver-tropic adeno-associated viral (AAV) vector carrying cassette coding hyperactive Padua factor IX (FIX) protein. It is being investigated for the treatment of hemophilia B.[A259048]
ZR202-CoV
go.drugbank.com/drugs/DB27995InvestigationalZR202-CoV is a biologic drug. ZR202-CoV is under investigation in clinical trial NCT05490108 (Evaluation of Safety and Immunogenicity of the Recombinant ZR202-CoV and ZR202a-CoV Vaccines in Adults.).
Categories: Complex MixturesAlcestobart
go.drugbank.com/drugs/DB28487InvestigationalAlcestobart is a biologic drug. … Alcestobart is under investigation in clinical trial NCT05909904 (A Study of Tislelizumab in Combination With Investigational Agents in Participants With Head and Neck Squamous Cell Carcinoma).
MVR-C5252
go.drugbank.com/drugs/DB30379InvestigationalMVR-C5252 is a biologic drug. MVR-C5252 is under investigation in clinical trial NCT06126744 (Open-Label Study to Evaluate the Safety, Tolerability and Efficacy of the Oncolytic HSV1 MVR-C5252).
ACCG-2671
go.drugbank.com/drugs/DB33945ExperimentalACCG-2671 is a small molecule drug. ACCG-2671 is under investigation in clinical trial NCT07815678 (First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671).
Enlonstobart
go.drugbank.com/drugs/DB21890InvestigationalEnlonstobart is a recombinant and fully-humanized immunoglobulin G4 monoclonal antibody. … [A274486] Enlonstobart is currently under investigation in clinical trial NCT06998771 (JSKN003 Combined Treatment of HER2-positive Gastric Cancer).
Progabide
go.drugbank.com/drugs/DB00837ExperimentalProgabide is an analog and prodrug of gamma-aminobutyric acid. It is commonly used in the treatment of epilepsy. It has agonistic activity for both the GABAA and GABAB receptors. … In clinical trials, progabide has been investigated for Parkinson's disease, schizophrenia, clinical depression and anxiety disorder; its therapeutic effectiveness in these conditions is not fully elucidated
Ginkgolide A
go.drugbank.com/drugs/DB06743ExperimentalNutraceuticalGinkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and immunological disorders.
Tovinontrine
go.drugbank.com/drugs/DB16193InvestigationalTovinontrine is an orally administered, highly selective phosphodiesterase 9 (PDE9) small molecule inhibitor. … Tovinontrine is under investigation in clinical trial NCT04474314 (A Study of IMR-687 in Subjects With Sickle Cell Disease).
Synonyms: 6-((3S,4S)-4-METHYL-1-(2-PYRIMIDINYLMETHYL)-3-PYRROLIDINYL)-3-(TETRAHYDRO-2H-PYRAN-4-YL)IMIDAZO(1,5-A)PYRAZIN-8(7H)-ONE, 6-[(3S,4S-4-methyl-1-(pyrimidin-2-ylmethyl)pyrrolidin-3-yl]-3-tetrahydropyran-4-yl-7H-imadazo[1,5-a]pyrazin-8-one