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Displaying results 8961 - 8970 of 10000 in total
  1. Drug

    Dihydro-alpha-ergocryptine

    go.drugbank.com/drugs/DB11274
    Approved

    These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino acid replacement from leucine to isoleucine. … Alpha-dihydroergocryptine approved drug product is as a part of an ergoloid mixture. To know more about this mixture, please visit [DB01049]

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: α-dihydroergocryptine, dihydro-α-ergocryptine
  2. Drug

    Alectinib

    go.drugbank.com/drugs/DB11363
    ApprovedInvestigational

    Alectinib is a second generation oral drug that selectively inhibits the activity of anaplastic lymphoma kinase (ALK) tyrosine kinase. … It is specifically used in the treatment of non-small cell lung cancer (NSCLC) expressing the ALK-EML4 (echinoderm microtubule-associated protein-like 4) fusion protein that causes proliferation of NSCLC

    Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein inhibitorsSynonyms: 9-ethyl-6,6-dimethyl-8-[4-(morpholin-4-yl)piperidin-1-yl]-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile
  3. Drug

    Maropitant

    go.drugbank.com/drugs/DB11427
    ExperimentalVet approved

    Maropitant, used as maropitant citrate, is a neurokinin receptor antagonist, which was developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs.

    Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  4. Drug

    Oclacitinib

    go.drugbank.com/drugs/DB11441
    ExperimentalVet approved

    Categories: Heterocyclic Compounds, 1-Ring, Janus Kinase 1, antagonists & inhibitors
  5. Drug

    Bunamidine

    go.drugbank.com/drugs/DB11501
    ExperimentalVet approved

    Bunamidine is a veterinary anti-platyhelmintic agent used for taenia infestations.

    Synonyms: N,N-Dibutyl-4-(hexyloxy)-1-naphthamidine, N,N-Dibutyl-4-hexyloxy-1-naphthamidin
  6. Drug

    Cefovecin

    go.drugbank.com/drugs/DB11505
    ExperimentalVet approved

    Cefovecin is a cephalosporin antibiotic used for the treatment of skin infections in cats and dogs. … It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs.

    Categories: Heterocyclic Compounds, 2-Ring
  7. Drug

    Zolazepam

    go.drugbank.com/drugs/DB11555
    ExperimentalVet approved

    Zolazepam is a pyrazolodiazepinone derivative used as an anaesthetic in veterinary medicine.

    Categories: Heterocyclic Compounds, 2-Ring
  8. Drug

    Grazoprevir

    go.drugbank.com/drugs/DB11575
    Approved

    Grazoprevir is an inhibitor of NS3/4A, a serine protease enzyme, encoded by HCV genotypes 1 and 4 [synthesis]. … in combination with [DB11574] for genotypes 1a, 1b, and 4 of Hepatitis C [A19593].

    Mixtures: ZEPATIER® TABLETAS RECUBIERTASCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates
  9. Drug

    Asunaprevir

    go.drugbank.com/drugs/DB11586
    ApprovedWithdrawn

    Asunaprevir, also named BMS-650032, is a potent hepatitis C virus (HCV) NS3 protease inhibitor. … It has been shown to have a very high efficacy in dual-combination regimens with daclatasvir in patients chronically infected with HCV genotype 1b.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: SUNVEPRA® 100MG CÁPSULAS BLANDAS
  10. Drug

    Domiphen

    go.drugbank.com/drugs/DB11594
    Approved

    Domiphen bromide is a quaternary ammonium compound that is predominantly employed as a topically administered antiseptic agent.

    Synonyms: 1-dodecanaminium, n,n-dimethyl-n-(2-phenoxyethyl), Dodecyldimethyl(2-phenoxyethyl)ammonium