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Displaying results 891 - 900 of 10000 in total
  1. Drug

    BW-A 58C

    go.drugbank.com/drugs/DB06740
    Experimental

    BW-A 58C, also known as 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, is an experimental naphthoquinone antimalarial drug which undergoes extensive alkyl hydroxylation to a single t-butylhydroxy … metabolite in man in vivo and also in human liver microsomes, where this is catalysed primarily by a 54 kDa CYP2C9 form of cytochrome P450, P450hB20-27.

    Synonyms: 2-(4'-t-Butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone, 2-(4-tert-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinoneCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inhibitors
  2. Drug

    (S)-2-((S)-3-isobutyl-2,5-dioxo-4-quinolin-3-ylmethyl-[1,4]diazepan-1yl)-N-methyl-3-naphtalen-2-yl-propionamide

    go.drugbank.com/drugs/DB04724
    Experimental

    Synonyms: (S)-2-((S)-3-isobutyl-2,5-dioxo-4-quinolin-3-ylmethyl-[1,4]diazepan-1yl)-N-methyl-3-naphtalen-2-yl-propionamide
  3. Drug

    3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide

    go.drugbank.com/drugs/DB07252
    Experimental

    Synonyms: 3-({4-[(5-chloro-1,3-benzodioxol-4-yl)amino]pyrimidin-2-yl}amino)benzenesulfonamide
  4. Drug

    (3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE

    go.drugbank.com/drugs/DB07964
    Experimental

    Synonyms: (3S)-4-{[4-(BUT-2-YNYLOXY)PHENYL]SULFONYL}-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE
  5. Drug

    [4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID

    go.drugbank.com/drugs/DB08513
    Experimental

    Synonyms: [4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID
  6. Drug

    N'-(2s,3r)-3-Amino-4-Cyclohexyl-2-Hydroxy-Butano-N-(4-Methylphenyl)Hydrazide

    go.drugbank.com/drugs/DB03086
    Experimental

    Synonyms: N'-(2s,3r)-3-Amino-4-Cyclohexyl-2-Hydroxy-Butano-N-(4-Methylphenyl)Hydrazide
  7. Drug

    Leflunomide

    go.drugbank.com/drugs/DB01097
    ApprovedInvestigational

    Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs, which are chemically and pharmacologically very heterogeneous.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 4-ISOXAZOLECARBOXAMIDE, 5-METHYL-N-(4-(TRIFLUOROMETHYL)PHENYL)-, 5-Methyl-N-(4-(trifluoromethyl)phenyl)-4-isoxazolecarboxamide
  8. Drug

    N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE

    go.drugbank.com/drugs/DB08025
    Experimental

    Synonyms: N-{2'-[(4-FLUOROPHENYL)AMINO]-4,4'-BIPYRIDIN-2-YL}-4-METHOXYCYCLOHEXANECARBOXAMIDE
  9. Drug

    Cisplatin

    go.drugbank.com/drugs/DB00515
    ApprovedInvestigational

    Cisplatin, cisplatinum or cis-diamminedichloroplatinum(II) (CDDP) is a platinum-based chemotherapy drug used to treat various types of cancers, including sarcomas, some carcinomas (e.g. small cell lung

    Synonyms: (SP-4-2)-DIAMMINEDICHLOROPLATINUM, PLATINUM, DIAMMINEDICHLORO-, (SP-4-2)-Categories: Cytochrome P-450 CYP2B6 Inhibitors, Cytochrome P-450 CYP2C9 Inhibitors
  10. Drug

    2-(4-Chlorophenyl)-5-Quinoxalinecarboxamide

    go.drugbank.com/drugs/DB03509
    Experimental

    Synonyms: 2-(4-Chlorophenyl)-5-QuinoxalinecarboxamideCategories: Heterocyclic Compounds, 2-Ring